We narrowed to 892 results for: CAN
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TypeBlog PostPublishedNov. 27, 2018, 2 p.m....plant compounds with antidiabetic properties that can ameliorate diabetics nephropathy, one of the major...generate a self renewable sensor, a bacterium that can sense contaminants and emit light as a response. ...complications of diabetes Gloria Otito Izu, PhD Candidate, University of Ibadan, Nigeriaunder supervision... of Ibadan, Nigeria Gloria Otito Izu is a PhD Candidate working under the supervision of Akindele Oluwatosin...fluorescent proteins and a new two-photon laser scanning microscope will allow Tsakanova to image cortical...extremophile microorganisms, biomarkers, and recently, cancer research related to space medicine. Now he aims...
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New and Upcoming Viral Vectors - May 2020
TypeBlog PostPublishedMay 28, 2020, 1:15 p.m....in target cells. While the various AAV serotypes can be used to achieve different patterns of expression...tissue targeting. While promoters and AAV serotypes can sometimes be used to target tissue types, recombinases... -
Synthesized by Ginkgo Bioworks, Shared by Addgene: SARS-CoV-2 Plasmids for Many Expression Systems
TypeBlog PostPublishedMay 19, 2020, 1:15 p.m....are continually added as they complete QC and you can find all available plasmids listed on Ginkgo’s collection...QC standards. If any concerns are identified, we can quickly put a hold on all orders and alert any scientists... -
Behind the scenes: Addgene’s new search engine and more
TypeBlog PostPublishedDec. 12, 2019, 2:22 p.m....Elasticsearch, a powerful open-source search engine that can scale to search millions of web resources and handle... to a user? Moreover, there are many ways a user can input their query — by directly typing terms in a... -
Learning Technical Skills at a Lab Central Workshop
TypeBlog PostPublishedFeb. 20, 2018, 2:30 p.m....learn from other biotech companies at workshops and can use what we learn to improve processes in the Addgene...Without proper processing, these small DNA strands can form concatemers in later steps. This new NEB kit...biotechnology company that uses neoantigen biology to treat cancer. My partner for the day was Julie from Novartis... -
Using CRISPR/Cas9 to Edit Disease Out of the Genome
TypeBlog PostPublishedJune 23, 2022, 1:15 p.m....Addgene co-op from Northeastern University. There can be no doubt that CRISPR/Cas9 technology has been ... for monogenetic diseases, the bulk of which you can find below. CRISPR for complex genetic diseases ....” Cystic fibrosis may not be the most likely candidate for gene therapy, however, because the disease...efficient enough for repair,” Doudna said. “And it can't be too hard to apply. These papers suggest it might... -
Building and Validating Recombinant Antibodies: A Case Study
TypeBlog PostPublishedApril 5, 2022, 1:20 p.m....non-recoverable, the stock of the mAb becomes limited, which can be a threat to future reproducibility. The Trimmer...based system for expression of R-mAbs is that it can easily be engineered. Like humans, mice express multiple... -
Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification
TypeBlog PostPublishedNov. 19, 2019, 2:08 p.m....OptoNB can bind, it co-localizes with its target at the cell membrane and when the OptoNB can’t bind, ...translocation. These results demonstrate that OptoNBs can be harnessed to regulate signaling pathways such ...signaling pathway, which is often over-activated in cancer due to its involved in cell proliferation and differentiation... -
Components of CRISPR/Cas9
TypeBlog PostPublishedFeb. 2, 2016, 5 p.m.... and the requirements of these different systems can vary (for example, xCas9 is a variant with increased...CRISPR, It's time to start thinking about how you can used them in your experiments. Use the following ...possible loci. Without binding to the guide RNA, Cas9 cannot cut. 2. Bind to target DNA in the presence of a... -
Hot Plasmids: Bacillus subtilis Libraries, iPSC Reprogramming, CRISPR Tools, & More!
TypeBlog PostPublishedDec. 11, 2017, 2:02 p.m....iPSC production, and CRISPR tools for plants. You can find additional hot plasmids in our quarterly newsletter...