We narrowed to 892 results for: CAN

1. X-CHIME: Context Dependent Germline Knockout in Immune Cells

   Type

   Blog Post

   Published

   Jan. 16, 2024, 6:13 p.m.

   ...vector containing a gRNA. These transduced stem cells can be implanted in irradiated recipients to create mice...phosphatases, PTPN1 and PTPN2, which are of interest as cancer immunotherapy targets but are embryonic lethal,...interested in improving CD8+ T cell responses to cancer.     References and resources References LaFleur...

2. New Viral Vectors - Fall 2024

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   Blog Post

   Published

   Oct. 3, 2024, 1:15 p.m.

   ...fold higher expression levels compared to AAV9. You can now target these cells with AAV-CAG-GFP packaged ...

3. The Stingy Scientist: How the Baby Gel Box Was Born

   Type

   Blog Post

   Published

   April 15, 2014, 3:11 p.m.

   ...run or risk minor electrocution.  These days you can buy small gel boxes, but none as small as the baby...to throw out chipped or imperfect equipment.  We can’t safely recycle these materials either.  Test tubes...

4. 9 Tips to Achieve Success in Academia

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   Blog Post

   Published

   April 1, 2014, 5:33 p.m.

   ...questions.   Advice for success in academia How can we shape our time in academia to maximize productivity...

5. In Living Color: The Skinny on In Vivo Imaging Tools

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   Blog Post

   Published

   March 27, 2014, 5:14 p.m.

   ...possible with conventional FPs. In addition, PA FPs can improve the achievable signal-to-background ratio...resolution images in vivo. “One of the reasons we can’t localize one cell at a depth of one centimeter with...

6. Tag Your Favorite Yeast Genes with Ease

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   Blog Post

   Published

   Nov. 19, 2013, 2:37 p.m.

   ...products is desired, as multiple selection markers can ensure that all desired tags have been integrated...

7. CRISPR Challenges: Standardization and Homology Directed Repair

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   Blog Post

   Published

   Feb. 14, 2018, 2:36 p.m.

   ...describe how a better understanding of Cas9 biophysics can help enhance HDR. CRISPR 101: Ribonucleoprotein (...

8. Addgene-Seeding Labs Plasmid Grant: Accelerating Science Globally - 5 Scientists, 4 Countries & 3 Continents!

   Type

   Blog Post

   Published

   July 18, 2017, 12:41 p.m.

   ...project the expression of isolated bacterial proteins can be achieved using a bacterial expression system such...expression of nutritionally and therapeutically significant proteins. In this project she aims to create ...essential, which means that the body requires them but cannot produce them. By using yeast integration vectors...

9. Addgene's a Nonprofit? Nonprofit Awareness Day 2017

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   Blog Post

   Published

   June 5, 2017, 3:19 p.m.

   ...term "nonprofit" is a bit misleading. Nonprofits can generate revenue (as Addgene does through materials...service organization like the Red Cross or the American Cancer Society, or maybe you think about a local food...do with their revenue. A nonprofit organization cannot distribute profits to private individuals through...

10. New Viral Vectors - Winter 2025

    Type

    Blog Post

    Published

    Jan. 28, 2025, noon

    ...serotypes. Not sure what to request? Addgene's Data Hub can help, with over 100 user-submitted viral vector reports...pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato AAV8 Molecular tool Massimo Scanziani New viral prep pAAV_hSyn1-SIO-stGtACR2-FusionRed...