We narrowed to 892 results for: CAN
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TypeBlog PostPublishedDec. 19, 2024, 2:15 p.m....been a privilege to find and share what stories we can, and to hear the stories others have to tell. "Also...
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The Future of Research Symposium Boston 2015
TypeBlog PostPublishedOct. 20, 2015, 2:30 p.m....the Future or Research Symposium Boston 2015 you can register here or live stream the event on October... -
Savvy Advocates Needed to Navigate a Scientific Enterprise in Flux
TypeBlog PostPublishedSept. 13, 2016, 2:30 p.m.... focused group of participants. More information can be found at http://futureofresearch.org/advocating-for-science-boston...and keynote by former congressman and CEO of the American Association for the Advancement of Science, Rush...solutions. The event also culminated in a joint American Society for Biochemistry and Molecular Biology...keynote address by former congressman and CEO of the American Association for the Advancement of Science, Rush... -
Plasmids 101: Terminators and PolyA signals
TypeBlog PostPublishedMarch 31, 2016, 2:30 p.m.... on a prokaryotic transcript is non-specific and can be added to any accessible 3' end. The presence of... -
Capturing a Moment with Marc Zimmer’s “The State of Science”
TypeBlog PostPublishedJuly 30, 2020, 1:15 p.m....real value here is seeing them all in one place. Can we address problems in scientific publishing without...posits the way science is being done has changed significantly over the last decade. He describes the detection... -
xCas9: Engineering a CRISPR Variant with PAM Flexibility
TypeBlog PostPublishedMarch 28, 2018, 6:52 p.m....only scratched the surface of modifications that can be made to Cas9. It is a pleasant surprise that selecting... -
Beyond the Blood Brain Barrier: PHP.B Enters the Central Nervous System Via the LY6A Receptor
TypeBlog PostPublishedJuly 23, 2019, 12:46 p.m.... from reaching their targets. The AAV9 serotype can breach the BBB following injection into the bloodstream...PHP.B to reach the CNS; yet LY6A is an unlikely candidate. It was discovered as an antigen upregulated on...this stretch of DNA, Ly6a seemed the most likely candidate due to its strong linkage to the PHP.B phenotype...variants could unintentionally limit the utility of candidate capsids. Are you interested in using AAV-PHP.... -
The Effect of COVID-19 on Liu Lab Plasmid Requests From Addgene Data
TypeBlog PostPublishedJuly 16, 2020, 1:15 p.m.... from just one lab, which limits how broadly one can interpret our analysis of COVID-19’s effect on scientific...months, pausing or terminating employment for a significant fraction of the workforce. Wet lab scientists...exponential decay model, with dips during weekends and significant holidays. Figure 4: Plasmid request trajectories...or labs placing orders for paper x on date t. We cannot use individual plasmid orders, because when a PI...Institute and Harvard University. Max Shen is a Ph.D. candidate at MIT. His research uses applied machine learning... -
Hot Biosensors 2022: Year-End Roundup
TypeBlog PostPublishedDec. 6, 2022, 2:15 p.m.... ITAM phosphorylated. To demonstrate that pYtags can be generalized to other RTKs of interest, they create...targets. Figure 6: A) Schematic of BeadScan platform for screening candidate biosensor variants for performance...tdTomato), they produce a temperature sensor that significantly outperforms previous designs. B-gTEMP is excitable...optimal conditions). While B-gTEMP itself is a significant improvement over previous temperature indicators... -
Plasmids 101: Common Lab E. coli Strains
TypeBlog PostPublishedNov. 7, 2014, 2:56 p.m.... cell still can methylate DNA hsdS(rk-,mk-) Unmethylated DNA not degraded, cell cannot methylate DNA... Mutation in galactose metabolism pathway Cells cannot grow on galactose only gyrA, gyrA96 DNA gyrase... lacY Lactose permease inactivated, lactose cannot be taken up by cell mcrA, mcrBC Inactivation ...