We narrowed to 214 results for: gnal

1. The Breast Cancer Microenvironment: A Tumor’s Backstage Team

   Type

   Blog Post

   Published

   Jan. 31, 2019, 1:32 p.m.

   ...increased expression of transforming growth factor-β signaling, possibly inducing the secretion of growth promoting...

2. Antibodies 101: Affinity Reagents

   Type

   Blog Post

   Published

   April 14, 2022, 1:15 p.m.

   ... extremely small at 12-15 kD but can have weak signals due to their monovalent nature. They are stable...

3. CRISPR 101: Cas9 vs. The Other Cas(s)

   Type

   Blog Post

   Published

   Dec. 8, 2022, 2:15 p.m.

   ...particularly useful in generating transient edits of signaling molecules (RNA) as opposed to permanent edits ...

4. Tagging Optogenetics and Chemogenetics Receptors: Fluorescent Proteins and Other Options

   Type

   Blog Post

   Published

   May 11, 2021, 1:15 p.m.

   ...receptor. However, in some cases the fluorescent signal may be critical for the experiment. Since the fused...

5. CRISPR Meets Synthetic Biology: A Conversation with MIT’s Christopher Voigt

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   Blog Post

   Published

   April 22, 2015, 2:06 p.m.

   ...circuits with many guide RNAs connected because the signal degrades at each layer. If we could fix these things...

6. Fluorescent Proteins 101: Introduction to FRET

   Type

   Blog Post

   Published

   June 27, 2017, 1:03 p.m.

   ...small molecules, detect cellular processes and signaling cascades, quantify mechanical tension (a molecular...

7. Plasmids for Endogenous Gene Tagging in Human Cells

   Type

   Blog Post

   Published

   April 6, 2017, 1:02 p.m.

   ... function and result in a ubiquitous background signal that makes it hard to visualize the precise location...

8. CRISPR Activators: A Comparison Between dCas9-VP64, SAM, SunTag, VPR, and More!

   Type

   Blog Post

   Published

   Oct. 6, 2020, 1:15 p.m.

   ...JS, Vale RD (2014) A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence...

9. Antibodies 101: ELISA (Enzyme-linked Immunosorbent Assay)

   Type

   Blog Post

   Published

   Aug. 24, 2021, 1:15 p.m.

   ...primary-secondary pair is used. This amplifies the signal as multiple secondary antibodies can bind to a ...

10. Hot Plasmids February 2024

    Type

    Blog Post

    Published

    Feb. 20, 2024, 2:45 p.m.

    ... to HIV TAT, Myc and SV40 Nuclear Localization Signals, and GFP. B) Workflow to assess Cas9-PAGE editing...

11. Savvy Advocates Needed to Navigate a Scientific Enterprise in Flux

    Type

    Blog Post

    Published

    Sept. 13, 2016, 2:30 p.m.

    ...outspoken in their opposition to unions, potentially signaling a rough road ahead for students interested in ...

12. Plasmids 101: Protein Expression

    Type

    Blog Post

    Published

    June 7, 2018, 1:17 p.m.

    ...University and is particularly interested in cell signaling and communication. She loves being able to help...

13. Cloning Mammalian Cells with the Agarose Method

    Type

    Blog Post

    Published

    Sept. 7, 2017, 12:17 p.m.

    ... Baltimore. She is particularly interested in signaling peptide maturation in neural and endocrine cells...

14. No Llamas Required - Synthetic Nanobodies Against Membrane Proteins

    Type

    Blog Post

    Published

    June 18, 2020, 1:15 p.m.

    ...Opto-Nanobodies: Using Light to Manipulate Cell Signaling and Protein Purification RANbodies: Reporter Nanobody...

15. The AAVantages of AAV in CRISPR Screens

    Type

    Blog Post

    Published

    Feb. 4, 2025, 2:15 p.m.

    ...delivery vector for gene therapy of human diseases. Signal Transduction and Targeted Therapy, 9(1). https:...

16. Magnetic Control of Proteins: More than a Dream

    Type

    Blog Post

    Published

    Sept. 24, 2024, 1:15 p.m.

    ...expressed and purified. Although a ~1% change in signal might not make a very powerful tool, it was promising...

17. Antibodies 101: Flow Compensation

    Type

    Blog Post

    Published

    May 16, 2024, 1:15 p.m.

    ...telling your cytometer to adjust the fluorescent signals by a specific value between the two channels. It...

18. Hot Plasmids and Viral Preps - May 2021

    Type

    Blog Post

    Published

    May 18, 2021, 1:15 p.m.

    ...enriched in the pre-synaptic terminal providing better signal to noise for imaging calcium dynamics in fine structures...

19. Plasmids 101: Multicistronic Vectors

    Type

    Blog Post

    Published

    Sept. 9, 2014, 8:20 p.m.

    ....0018556. Epub 2011 Apr 29.) PubMed. 5. Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ...

20. Drew Endy Introduces the Biobrick Public Agreement Plasmid Collection

    Type

    Blog Post

    Published

    Dec. 12, 2013, 3:35 p.m.

    ...typically invisible information into actionable signals. Let's say I wanted to detect every primary metabolite...