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We narrowed to 73 results for: Adm

Showing: 1 - 20 of 73 results

  2. Common Injection Routes in Mice

    Type
    Blog Post
    Published
    Jan. 22, 2025, 9:42 p.m.
    .... A. (2011). Administration of substances to laboratory animals: routes of administration and factors ...Intravenous (IV) injections are most commonly administered through the tail vein — many researchers will... the abdomen. They are a popular choice for administering different drugs and viral vectors. Like IV injections...suggests, in the muscle. Common uses include administering vaccines, pain meds, or other drugs. Identifying...injections are used when the substance being administered must be delivered to the central nervous system...requires a pipette. Since the substances are administered through the nose, they also pass through the...straight to the stomach. This technique involves administering medication through a feeding tube with a bulb...

  3. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    Published
    Oct. 12, 2023, 1:15 p.m.
    ...typically administered in the lateral tail vein or retro-orbital sinus. IT injections are administered in the...to have enhanced function after intravenous administration, distributing widely throughout the organism... expression, particularly in the liver, when administered intravenously. To address these limitations,...primarily derived from AAV9, the vectors have to be administered concurrently to minimize the impact of neutralizing...AAV9 and AAV1 serotypes, allowing sequential administration (Chen et al., 2023). High viral titer High ...applications. For example, AAV-PHP.eB is typically administered at a total dose between 1 x 1011 and 5 x 1011...find commonly used vector cargo designs and administration doses. Note: If capsid immunogenicity is a ...

  4. Finding Your Science Policy Path

    Type
    Blog Post
    Published
    Sept. 22, 2020, 1:15 p.m.
    ...Technology Policy Fellow at the Veterans Health Administration. “But, seriously, what even is science policy...Policy Fellow (STPF) at the Veterans Health Administration, I could never get one straight answer about...personal lens.  For me, the Veterans Health Administration was the perfect position because my science...Technology Policy Fellow at the Veterans Health Administration. Steph Guerra, PhD, is currently a AAAS Science...Technology Policy Fellow at the Veterans Health Administration where her work focuses on incentivizing the...

  5. Cas13d: Small RNA-targeting CRISPR enzymes for transcriptome engineering

    Type
    Blog Post
    Published
    May 3, 2018, 1:48 p.m.
    ...orthologs from “Anaerobic digester metagenome” (AdmCas13d) and Ruminococcus flavefaciens (nicknamed CasRx...Konermann et al. saw great results with CasRx and AdmCas13d fused to a nuclear localization signal (NLS). ...In a HEK293 mCherry reporter assay, CasRx and AdmCas13d produced 92% and 87% mCherry protein knockdown...

  6. Developing a cold tolerant E. coli using specialized chaperones

    Type
    Blog Post
    Published
    Jan. 28, 2020, 2:35 p.m.
    ...This post was contributed by Sreepadmanabh M, a member of the iGEM team from IISER Bhopal. Following ...gmail.com. Many thanks to our guest blogger Sreepadmanabh M from IISER Bhopal. All illustrations / figures...designed by our team member Kallol Mozumdar. Sreepadmanabh M is a member of the team from IISER Bhopal ...

  7. Will You Be My Mentor? Finding and Asking for Mentoring Support

    Type
    Blog Post
    Published
    Feb. 4, 2014, 3:50 p.m.
    ... “make the ask” once you have found someone you admire and want to learn from. Check out Joanne's Reddit...learn. Mentors can be senior to you or peers you admire.  If you see someone who gives a great talk, ask...path you are interested in following? Someone you admire for their insight and way of expressing it in meetings...

  8. March for Science

    Type
    Blog Post
    Published
    April 21, 2017, 2:30 p.m.
    ...general public agrees (5, 6). Many of the new administration’s actions, including taking down the climate...and the first federal budget request of this administration promises more cuts (3, 12, 13, 27). In order...Purged from Website The Washington Post: Trump administration tells EPA to freeze all grants, contracts The...

  9. Viral Vectors 101: AAV Serotypes and Tissue Tropism

    Type
    Blog Post
    Published
    Jan. 16, 2025, 3:42 p.m.
    ... that can target specific tissues, even when administered systemically, without causing disease? Recombinant...AAV serotypes varies by species and route of administration (Wu, Asokan, et al., 2006). Want to know if...reports on commonly used vector cargo designs and administration doses. Don't forget to submit your validation...

  11. Multifunctional Neural Fibers: Modulation from Gut to Brain

    Type
    Blog Post
    Published
    Aug. 31, 2023, 1 p.m.
    ...I often wonder about the gut-brain axis (admittedly for self-serving reasons – I want to understand my...neurological means like electric stimulation, drug administration, and optogenetics. Enter neural fibers! The...

  12. Predicting Adverse Reactions to Monoclonal Antibody Drugs

    Type
    Blog Post
    Published
    Feb. 13, 2024, 2:15 p.m.
    ...from cancer to autoimmune disorders. Antibodies administered as drugs are still immunogenic, meaning that...; and sequence of biologic product, mode of administration, and dose (Lu et.al., 2020).  Evaluating a ...

  13. AAV Q&A with Tim Miles

    Type
    Blog Post
    Published
    May 17, 2022, 1:15 p.m.
    ...antibodies become a prohibitive problem? A: Re-administration is a challenge for AAV due to the development...immunomodulation or immune suppression to allow AAV re-administration but I do not think the field has settled on...

  15. 5 Steps to Writing Grant Proposals for Grad Students

    Type
    Blog Post
    Published
    Feb. 11, 2014, 12:13 p.m.
    ...weeks before the RFA due date in order for the administrative side of the grant to be established. Take time... information, selection criteria, and award administration information. Carefully read over all parts ...

  16. Adeno Associated Virus (AAV) for Cell and Gene Therapy

    Type
    Blog Post
    Published
    Nov. 7, 2017, 1:59 p.m.
    ...deliver it and identifying a suitable route of administration. However, until recently safe delivery of nucleic...2008. Following a single dose of subretinal administration of rAAV2 carrying the human gene RPE65, patients...

  17. Viral Vectors 101: Virus Safety

    Type
    Blog Post
    Published
    June 22, 2023, 1:15 p.m.
    ...of following your lab’s biohazard policies. Administering Virus Many virus experiments involve needles...accidents is not following safety protocols.) If administering virus to mice, part of your preparation should...

  18. A Career in Grants: How To Become a Grant Professional

    Type
    Blog Post
    Published
    Aug. 20, 2015, 2:30 p.m.
    ...expertise in grant writing, grant management, grant administration, and grant evaluation are available through... expertise in grant project management from administration and fundraising to program design and evaluation...

  19. Changing Labor Laws Bring Increased Postdoc Wages

    Type
    Blog Post
    Published
    Oct. 25, 2016, 2:30 p.m.
    ... hard to find and this is partly due to the administration of postdocs, often at a departmental level ...level rather than being centrally administered, which leads to many complications, including the inability...

  20. Replacing Paper: Tips for Choosing an Electronic lab Notebook

    Type
    Blog Post
    Published
    July 10, 2018, 1:08 p.m.
    ...down certain notes or brainstorm, but we have to admit that paper-based record keeping barely copes with...Researchers spend 40% of their time on tedious administrative tasks that drain resources from the actual ...
Showing: 1 - 20 of 73 results