Expanding the Targeting Scope and Editing Efficiency of Adenine Base Editors
Type
Blog Post
Published
March 17, 2020, 1:32 p.m.
...represents the major difference between PACE and PANCE: for PANCE the phage progeny is not diluted out but gets...PACE) and Phage-Assisted Non-Continuous Evolution (PANCE) selection systems to engineer better and faster...selection, and replications per day.
The PACE and PANCE systems use M13 bacteriophage, which rely on the...and flexible adenine base editor
Lower-stringency PANCE, followed by higher stringency PACE, resulted in...