Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation
Type
Blog Post
Published
May 21, 2020, 1:15 p.m.
...recombination sites. These sites are target sequences of PhiC31. In the SPARC system, attP sites are located on...is not expressed and the cells are not labeled.
PhiC31, a recombinase. It specifically integrates an attP...attP site into an attB site. In the SPARC system, PhiC31 irreversibly recombines one of the two competing...labeling in a variety of fly cell types. Because the PhiC31 recombinase can work in other model organisms including...