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Neocortical excitation/inhibition balance in information processing and social dysfunction.
Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein J, Paz JT, Stehfest K, Fudim R, Ramakrishnan C, Huguenard JR, Hegemann P, Deisseroth K
Nature. 2011 Jul 27;477(7363):171-8. doi: 10.1038/nature10360.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
35497pAAV-Ef1a-DIO C1V1 (t/t)-TS-EYFPAAV expression of Ef1a-driven, cre-dependent, chimeric opsin variant C1V1 (E122T/E162T) for fast and potent optical excitation at red-shifted wavelengths.
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35498pAAV-Ef1a-DIO C1V1 (t/t)-TS-mCherryAAV expression of Ef1a-driven, cre-dependent, chimeric opsin variant C1V1 (E122T/E162T) for fast and potent optical excitation at red-shifted wavelengths.
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35499pAAV-CaMKIIa-C1V1 (t/t)-TS-EYFPAAV expression of CaMKII-driven chimeric opsin variant C1V1 (E122T/E162T) for fast and potent optical excitation at red-shifted wavelengths.
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35500pAAV-CaMKIIa-C1V1 (t/t)-TS-mCherryAAV expression of CaMKII-driven chimeric opsin variant C1V1 (E122T/E162T) for fast and potent optical excitation at red-shifted wavelengths.
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35501pAAV-CaMKIIa-hChR2(C128S/D156A)-EYFPAAV expression of CaMKII-driven stabilized step function opsin (SSFO) for optogenetic activation.
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35502pAAV-CaMKIIa-hChR2(C128S/D156A)-mCherryAAV expression of CaMKII-driven stabilized step function opsin (SSFO) for optogenetic activation.
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35503pAAV-Ef1a-DIO hChR2(C128S/D156A)-EYFPAAV expression of Ef1a-driven, cre-dependent, stabilized step function opsin (SSFO) for optogenetic activation.
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35504pAAV-Ef1a-DIO hChR2(C128S/D156A)-mCherryAAV expression of Ef1a-driven, cre-dependent, stabilized step function opsin (SSFO) for optogenetic activation.
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