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pcDNA3 flag p53 Citations (57)

Originally described in: Induction of p53-independent apoptosis by simian virus 40 small t antigen.
Gjoerup O, Zaveri D, Roberts TM J Virol. 2001 Oct . 75(19):9142-55.
PubMed Journal

Articles Citing pcDNA3 flag p53

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy. Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, Planelles V, Maggirwar SB, Dewhurst S, Kim B. Retrovirology. 2008 Jan 31;5:11. doi: 10.1186/1742-4690-5-11. PubMed
USP10 regulates p53 localization and stability by deubiquitinating p53. Yuan J, Luo K, Zhang L, Cheville JC, Lou Z. Cell. 2010 Feb 5;140(3):384-96. doi: 10.1016/j.cell.2009.12.032. Epub 2010 Jan 21. PubMed
Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression. Wu L, Ma CA, Zhao Y, Jain A. J Biol Chem. 2011 Jan 21;286(3):2236-44. doi: 10.1074/jbc.M110.174755. Epub 2010 Oct 19. PubMed
Formulation of chitosan-TPP-pDNA nanocapsules for gene therapy applications. Gaspar VM, Sousa F, Queiroz JA, Correia IJ. Nanotechnology. 2011 Jan 7;22(1):015101. doi: 10.1088/0957-4484/22/1/015101. Epub 2010 Dec 6. PubMed
Gain of function of mutant p53 by coaggregation with multiple tumor suppressors. Xu J, Reumers J, Couceiro JR, De Smet F, Gallardo R, Rudyak S, Cornelis A, Rozenski J, Zwolinska A, Marine JC, Lambrechts D, Suh YA, Rousseau F, Schymkowitz J. Nat Chem Biol. 2011 May;7(5):285-95. doi: 10.1038/nchembio.546. Epub 2011 Mar 27. PubMed
PKCzeta mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation. Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J. J Cell Biol. 2011 May 30;193(5):867-84. doi: 10.1083/jcb.201010051. PubMed
p53 regulates the expression of human angiotensin II AT(2) receptor interacting protein (ATIP1) gene. Chen Z, Liu X, Wang C, Jin Y, Wang Y, Wang A, Zhou X. Oncol Lett. 2011 Sep;2(5):919-922. PubMed
Alternative splicing within the elk-1 5' untranslated region serves to modulate initiation events downstream of the highly conserved upstream open reading frame 2. Rahim G, Araud T, Jaquier-Gubler P, Curran J. Mol Cell Biol. 2012 May;32(9):1745-56. doi: 10.1128/MCB.06751-11. Epub 2012 Feb 21. PubMed
Plasmid DNA microgels for a therapeutical strategy combining the delivery of genes and anticancer drugs. Costa D, Valente AJ, Miguel MG, Queiroz J. Macromol Biosci. 2012 Sep;12(9):1243-52. doi: 10.1002/mabi.201200096. Epub 2012 Jul 26. PubMed
pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737. Bertin-Ciftci J, Barre B, Le Pen J, Maillet L, Couriaud C, Juin P, Braun F. Cell Death Differ. 2013 May;20(5):755-64. doi: 10.1038/cdd.2013.6. Epub 2013 Feb 22. PubMed
The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex. Feldman DE, Chen C, Punj V, Machida K. PLoS One. 2013;8(2):e57312. doi: 10.1371/journal.pone.0057312. Epub 2013 Feb 27. PubMed
Selective purification of supercoiled p53-encoding pDNA with L-methionine-agarose matrix. Valente JF, Sousa A, Queiroz JA, Sousa F. Anal Biochem. 2014 Aug 15;459:61-9. doi: 10.1016/j.ab.2014.05.011. Epub 2014 May 23. PubMed
Rhodamine based plasmid DNA nanoparticles for mitochondrial gene therapy. Santos J, Sousa F, Queiroz J, Costa D. Colloids Surf B Biointerfaces. 2014 Sep 1;121:129-40. doi: 10.1016/j.colsurfb.2014.06.003. Epub 2014 Jun 7. PubMed
Epibrassinolide-induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate cancer cells. Obakan P, Arisan ED, Coker-Gurkan A, Palavan-Unsal N. Prostate. 2014 Dec;74(16):1622-33. doi: 10.1002/pros.22879. Epub 2014 Sep 11. PubMed
Plasmid DNA nanogels as photoresponsive materials for multifunctional bio-applications. Costa D, Valente AJ, Queiroz J. J Biotechnol. 2015 May 20;202:98-104. doi: 10.1016/j.jbiotec.2014.10.033. Epub 2014 Nov 20. PubMed
Starvation promotes REV1 SUMOylation and p53-dependent sensitization of melanoma and breast cancer cells. Shim HS, Wei M, Brandhorst S, Longo VD. Cancer Res. 2015 Mar 15;75(6):1056-67. doi: 10.1158/0008-5472.CAN-14-2249. Epub 2015 Jan 22. PubMed
WIP1 phosphatase as a potential therapeutic target in neuroblastoma. Richter M, Dayaram T, Gilmartin AG, Ganji G, Pemmasani SK, Van Der Key H, Shohet JM, Donehower LA, Kumar R. PLoS One. 2015 Feb 6;10(2):e0115635. doi: 10.1371/journal.pone.0115635. eCollection 2015. PubMed
Stimuli-responsive polyamine-DNA blend nanogels for co-delivery in cancer therapy. Costa D, Valente AJ, Queiroz J. Colloids Surf B Biointerfaces. 2015 Aug 1;132:194-201. doi: 10.1016/j.colsurfb.2015.04.064. Epub 2015 May 11. PubMed
The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death. Bock FJ, Tanzer MC, Haschka MD, Krumschnabel G, Sohm B, Goetsch K, Kofler R, Villunger A. Sci Rep. 2015 Jun 11;5:11268. doi: 10.1038/srep11268. PubMed
p53-Encoding pDNA Purification by Affinity Chromatography for Cancer Therapy. Sousa A, Queiroz JA, Sousa F. Methods Mol Biol. 2015;1317:109-24. doi: 10.1007/978-1-4939-2727-2_7. PubMed
Polyethylenimine coated plasmid DNA-surfactant complexes as potential gene delivery systems. Costa D, Briscoe WH, Queiroz J. Colloids Surf B Biointerfaces. 2015 Jun 8;133:156-163. doi: 10.1016/j.colsurfb.2015.06.005. PubMed
p53 regulates the mevalonate pathway in human glioblastoma multiforme. Laezza C, D'Alessandro A, Di Croce L, Picardi P, Ciaglia E, Pisanti S, Malfitano AM, Comegna M, Faraonio R, Gazzerro P, Bifulco M. Cell Death Dis. 2015 Oct 15;6:e1909. doi: 10.1038/cddis.2015.279. PubMed
Affinity analysis and application of dipeptides derived from l-tyrosine in plasmid purification. Ferreira S, Carvalho J, Valente JF, Corvo MC, Cabrita EJ, Sousa F, Queiroz JA, Cruz C. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Dec 1;1006:47-58. doi: 10.1016/j.jchromb.2015.10.025. Epub 2015 Oct 23. PubMed
PACS-2 mediates the ATM and NF-kappaB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Barroso-Gonzalez J, Auclair S, Luan S, Thomas L, Atkins KM, Aslan JE, Thomas LL, Zhao J, Zhao Y, Thomas G. Cell Death Differ. 2016 Mar 4. doi: 10.1038/cdd.2016.23. PubMed
TRIM65 negatively regulates p53 through ubiquitination. Li Y, Ma C, Zhou T, Liu Y, Sun L, Yu Z. Biochem Biophys Res Commun. 2016 Apr 22;473(1):278-82. doi: 10.1016/j.bbrc.2016.03.093. Epub 2016 Mar 21. PubMed
An inducible long noncoding RNA amplifies DNA damage signaling. Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. Nat Genet. 2016 Nov;48(11):1370-1376. doi: 10.1038/ng.3673. Epub 2016 Sep 26. PubMed
A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer. Zhai N, Xia Y, Yin R, Liu J, Gao F. Onco Targets Ther. 2016 Sep 16;9:5713-5720. eCollection 2016. PubMed
HOP expression is regulated by p53 and RAS and characteristic of a cancer gene signature. Mattison SA, Blatch GL, Edkins AL. Cell Stress Chaperones. 2016 Dec 16. PubMed
Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression. Xu WW, Li B, Guan XY, Chung SK, Wang Y, Yip YL, Law SY, Chan KT, Lee NP, Chan KW, Xu LY, Li EM, Tsao SW, He QY, Cheung AL. Nat Commun. 2017 Feb 10;8:14399. doi: 10.1038/ncomms14399. PubMed
An efficient rapid system for assaying HBx-mediated transactivation. Zhou X, Shi H, Yang S, Sun P. Biotechnol Lett. 2017 Jul;39(7):1091-1099. doi: 10.1007/s10529-017-2334-1. Epub 2017 Apr 6. PubMed
p53 target miR-29c-3p suppresses colon cancer cell invasion and migration through inhibition of PHLDB2. Chen G, Zhou T, Li Y, Yu Z, Sun L. Biochem Biophys Res Commun. 2017 May 20;487(1):90-95. doi: 10.1016/j.bbrc.2017.04.023. Epub 2017 Apr 7. PubMed
The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation. Nguyen DTT, Richter D, Michel G, Mitschka S, Kolanus W, Cuevas E, Gregory Wulczyn F. Cell Death Differ. 2017 Jun;24(6):1063-1078. doi: 10.1038/cdd.2017.54. Epub 2017 Apr 21. PubMed
Targeting of Cellular Organelles by Fluorescent Plasmid DNA Nanoparticles. Costa D, Costa C, Caldeira M, Cortes L, Queiroz JA, Cruz C. Biomacromolecules. 2017 Sep 11;18(9):2928-2936. doi: 10.1021/acs.biomac.7b00877. Epub 2017 Aug 25. PubMed
Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-kappaB and p53 signaling pathways. Ullah K, Rosendahl AH, Izzi V, Bergmann U, Pihlajaniemi T, Maki JM, Myllyharju J. Sci Rep. 2017 Dec 8;7(1):17220. doi: 10.1038/s41598-017-17376-0. PubMed
MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development. Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, Chen Q, Wei L, Wang Y, Chen H. J Exp Clin Cancer Res. 2018 Feb 13;37(1):28. doi: 10.1186/s13046-018-0693-7. PubMed
Finding the ideal polyethylenimine-plasmid DNA system for co-delivery of payloads in cancer therapy. Costa D, Valente AJM, Queiroz JA, Sousa A. Colloids Surf B Biointerfaces. 2018 Oct 1;170:627-636. doi: 10.1016/j.colsurfb.2018.06.063. Epub 2018 Jun 30. PubMed
Synergistic effect of Nutlin-3 combined with MG-132 on schwannoma cells through restoration of merlin and p53 tumour suppressors. Chen H, Xue L, Huang H, Wang H, Zhang X, Zhu W, Wang Z, Wang Z, Wu H. EBioMedicine. 2018 Oct;36:252-265. doi: 10.1016/j.ebiom.2018.09.042. Epub 2018 Sep 28. PubMed
Combinatory inhibition of TRIM65 and MDM2 in lung cancer cells. Chen G, Zhou T, Liu Y, Yu Z. Biochem Biophys Res Commun. 2018 Nov 30;506(3):698-702. doi: 10.1016/j.bbrc.2018.10.130. Epub 2018 Oct 27. PubMed
Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperone protein, has broad oncogenic properties. Zella D, Curreli S, Benedetti F, Krishnan S, Cocchi F, Latinovic OS, Denaro F, Romerio F, Djavani M, Charurat ME, Bryant JL, Tettelin H, Gallo RC. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E12005-E12014. doi: 10.1073/pnas.1815660115. Epub 2018 Dec 3. PubMed
DoE to improve supercoiled p53-pDNA purification by O-phospho-l-tyrosine chromatography. Valente JFA, Sousa A, Queiroz JA, Sousa F. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Jan 15;1105:184-192. doi: 10.1016/j.jchromb.2018.12.002. Epub 2018 Dec 15. PubMed
A co-delivery platform based on plasmid DNA peptide-surfactant complexes: formation, characterization and release behavior. Costa D, Albuquerque T, Queiroz JA, Valente AJM. Colloids Surf B Biointerfaces. 2019 Jun 1;178:430-438. doi: 10.1016/j.colsurfb.2019.03.029. Epub 2019 Mar 16. PubMed
Optimization of peptide-plasmid DNA vectors formulation for gene delivery in cancer therapy exploring design of experiments. Sousa A, Almeida AM, Faria R, Konate K, Boisguerin P, Queiroz JA, Costa D. Colloids Surf B Biointerfaces. 2019 Nov 1;183:110417. doi: 10.1016/j.colsurfb.2019.110417. Epub 2019 Aug 6. PubMed
Cancer gene therapy mediated by RALA/plasmid DNA vectors: Nitrogen to phosphate groups ratio (N/P) as a tool for tunable transfection efficiency and apoptosis. Neves AR, Sousa A, Faria R, Albuquerque T, Queiroz JA, Costa D. Colloids Surf B Biointerfaces. 2020 Jan 1;185:110610. doi: 10.1016/j.colsurfb.2019.110610. Epub 2019 Oct 24. PubMed
p53 regulates katanin-p60 promoter in HCT 116 cells. Kirimtay K, Selcuk E, Kelle D, Erman B, Karabay A. Gene. 2020 Feb 15;727:144241. doi: 10.1016/j.gene.2019.144241. Epub 2019 Nov 9. PubMed
The molecular targets of diclofenac differs from ibuprofen to induce apoptosis and epithelial mesenchymal transition due to alternation on oxidative stress management p53 independently in PC3 prostate cancer cells. Arisan ED, Akar RO, Rencuzogullari O, Obakan Yerlikaya P, Coker Gurkan A, Akin B, Dener E, Kayhan E, Palavan Unsal N. Prostate Int. 2019 Dec;7(4):156-165. doi: 10.1016/j.prnil.2019.09.003. Epub 2019 Nov 14. PubMed
Purification of supercoiled p53-encoding plasmid using an arginine-modified macroporous support. Valente JFA, Sousa A, Azevedo GA, Queiroz JA, Sousa F. J Chromatogr A. 2020 May 10;1618:460890. doi: 10.1016/j.chroma.2020.460890. Epub 2020 Jan 15. PubMed
Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway. Gerakopoulos V, Ngo P, Tsiokas L. Life Sci Alliance. 2020 Jul 10;3(9). pii: 3/9/e202000750. doi: 10.26508/lsa.202000750. Print 2020 Sep. PubMed
Enhanced Biosynthesis of Plasmid DNA from Escherichia coli Applying Experimental Design. Passarinha LA. Methods Mol Biol. 2021;2197:135-150. doi: 10.1007/978-1-0716-0872-2_7. PubMed
Improved ionic-liquid-functionalized macroporous supports able to purify nucleic acids in one step. Neves MC, Pereira P, Pedro AQ, Martins JC, Trindade T, Queiroz JA, Freire MG, Sousa F. Mater Today Bio. 2020 Nov 11;8:100086. doi: 10.1016/j.mtbio.2020.100086. eCollection 2020 Sep. PubMed
p53 affects epigenetic signature on SOCS1 promoter in response to TLR4 inhibition. Sheikh T, Sen E. Cytokine. 2021 Apr;140:155418. doi: 10.1016/j.cyto.2020.155418. Epub 2021 Jan 18. PubMed
Effect of Plasmid DNA Size on Chitosan or Polyethyleneimine Polyplexes Formulation. Valente JFA, Pereira P, Sousa A, Queiroz JA, Sousa F. Polymers (Basel). 2021 Mar 5;13(5). pii: polym13050793. doi: 10.3390/polym13050793. PubMed
Development of Tailor-Made Dendrimer Ternary Complexes for Drug/Gene Co-Delivery in Cancer. Neves AR, Albuquerque T, Faria R, Paul M, Biswas S, Sousa A, Costa D. Pharmaceutics. 2021 Aug 13;13(8). pii: pharmaceutics13081256. doi: 10.3390/pharmaceutics13081256. PubMed
The Influence of Circadian Rhythm on Cancer Cells Targeting and Transfection Efficiency of a Polycation-Drug/Gene Delivery Vector. Albuquerque T, Neves AR, Quintela T, Costa D. Polymers (Basel). 2022 Feb 10;14(4). pii: polym14040681. doi: 10.3390/polym14040681. PubMed
Complementary omics strategies to dissect p53 signaling networks under nutrient stress. Galhuber M, Michenthaler H, Heininger C, Reinisch I, Nossing C, Krstic J, Kupper N, Moyschewitz E, Auer M, Heitzer E, Ulz P, Birner-Gruenberger R, Liesinger L, Lenihan-Geels GN, Oster M, Spreitzer E, Zenezini Chiozzi R, Schulz TJ, Schupp M, Madl T, Heck AJR, Prokesch A. Cell Mol Life Sci. 2022 May 30;79(6):326. doi: 10.1007/s00018-022-04345-8. PubMed
Development of WRAP5 Peptide Complexes for Targeted Drug/Gene Co-Delivery toward Glioblastoma Therapy. Neves AR, Albuquerque T, Faria R, Goncalves AM, Santos C, Vives E, Boisguerin P, Passarinha LA, Sousa A, Costa D. Pharmaceutics. 2022 Oct 18;14(10):2213. doi: 10.3390/pharmaceutics14102213. PubMed
Arginine-Modified 3D-Printed Chromatographic Supports. Valente JFA, Carreira TS, Dias JR, Sousa F, Alves N. Pharmaceutics. 2022 Oct 23;14(11):2266. doi: 10.3390/pharmaceutics14112266. PubMed
Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington's disease. Mansky RH, Greguske EA, Yu D, Zarate N, Intihar TA, Tsai W, Brown TG, Thayer MN, Kumar K, Gomez-Pastor R. Cell Rep. 2023 Mar 28;42(3):112198. doi: 10.1016/j.celrep.2023.112198. Epub 2023 Mar 3. PubMed

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