PLJR962 Citations (20)
Originally described in: Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM Nat Microbiol. 2017 Feb 6;2:16274. doi: 10.1038/nmicrobiol.2016.274. PubMed Journal
Articles Citing PLJR962
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| An ABC transporter Wzm-Wzt catalyzes translocation of lipid-linked galactan across the plasma membrane in mycobacteria. Savkova K, Huszar S, Barath P, Pakanova Z, Kozmon S, Vancova M, Tesarova M, Blasko J, Kalinak M, Singh V, Kordulakova J, Mikusova K. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17). pii: 2023663118. doi: 10.1073/pnas.2023663118. PubMed |
| Mycobacteria Tolerate Carbon Monoxide by Remodeling Their Respiratory Chain. Bayly K, Cordero PRF, Kropp A, Huang C, Schittenhelm RB, Grinter R, Greening C. mSystems. 2021 May 11;6(3). pii: 6/3/e01292-20. doi: 10.1128/mSystems.01292-20. PubMed |
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.
Bosch B, DeJesus MA, Poulton NC, Zhang W, Engelhart CA, Zaveri A, Lavalette S, Ruecker N, Trujillo C, Wallach JB, Li S, Ehrt S, Chait BT, Schnappinger D, Rock JM.
Cell. 2021 Jul 16. pii: S0092-8674(21)00824-2. doi: 10.1016/j.cell.2021.06.033.
PubMed
Associated Plasmids |
| CRISPR Inhibition of Essential Peptidoglycan Biosynthesis Genes in Mycobacterium abscessus and Its Impact on beta-Lactam Susceptibility. Kurepina N, Chen L, Composto K, Rifat D, Nuermberger EL, Kreiswirth BN. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0009322. doi: 10.1128/aac.00093-22. Epub 2022 Mar 21. PubMed |
| RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness. Griego A, Douche T, Gianetto QG, Matondo M, Manina G. iScience. 2022 Apr 12;25(5):104233. doi: 10.1016/j.isci.2022.104233. eCollection 2022 May 20. PubMed |
| Mycobacterium tuberculosis sRNA MTS2823 regulates the growth of the multidrug-resistant strain in macrophages. Chen Z, Jiang W, Zhang M, Yu B, Li W, Liu J, Ai F. FEMS Microbiol Lett. 2022 Nov 23;369(1):fnac106. doi: 10.1093/femsle/fnac106. PubMed |
| CRISPRi-mediated characterization of novel anti-tuberculosis targets: Mycobacterial peptidoglycan modifications promote beta-lactam resistance and intracellular survival. Silveiro C, Marques M, Olivenca F, Pires D, Mortinho D, Nunes A, Pimentel M, Anes E, Catalao MJ. Front Cell Infect Microbiol. 2023 Mar 15;13:1089911. doi: 10.3389/fcimb.2023.1089911. eCollection 2023. PubMed |
| CRISPR Interference-Based Inhibition of MAB_0055c Expression Alters Drug Sensitivity in Mycobacterium abscessus. Nguyen TQ, Heo BE, Park Y, Jeon S, Choudhary A, Moon C, Jang J. Microbiol Spectr. 2023 Jun 15;11(3):e0063123. doi: 10.1128/spectrum.00631-23. Epub 2023 May 9. PubMed |
A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus.
Neo DM, Clatworthy AE, Hung DT.
J Bacteriol. 2024 Mar 21;206(3):e0033523. doi: 10.1128/jb.00335-23. Epub 2024 Feb 6.
PubMed
Associated Plasmids |
| MSMEG_0918 is not Essential for the Growth of Mycobacteriumsmegmatis. Bedru E, Bhagwat A, Parish T. MicroPubl Biol. 2024 Feb 6;2024:10.17912/micropub.biology.000891. doi: 10.17912/micropub.biology.000891. eCollection 2024. PubMed |
| Insertion sequence transposition activates antimycobacteriophage immunity through an lsr2-silenced lipid metabolism gene island. Li Y, Wei Y, Guo X, Li X, Lu L, Hu L, He ZG. mLife. 2024 Mar 26;3(1):87-100. doi: 10.1002/mlf2.12106. eCollection 2024 Mar. PubMed |
| CRISPR Interference-Mediated Silencing of the mmpL3 Gene in Mycobacterium smegmatis and Its Impact on Antimicrobial Susceptibility. Yuliani Y, Ilmi AFN, Petsong S, Sawatpanich A, Chirakul S, Chatsuwan T, Palaga T, Rotcheewaphan S. Antibiotics (Basel). 2024 May 24;13(6):483. doi: 10.3390/antibiotics13060483. PubMed |
| The CRISPR-dCas9 interference system suppresses inhA gene expression in Mycobacterium smegmatis. Singpanomchai N, Ratthawongjirakul P. Sci Rep. 2024 Oct 30;14(1):26116. doi: 10.1038/s41598-024-77442-2. PubMed |
| GrcC1 mediates low-level resistance to multiple drugs in M. marinum, M. abscessus, and M. smegmatis. Fang C, Zhang H, He J, Tian X, Zeng S, Han X, Wang S, Yusuf B, Hu J, Zhong N, Gao Y, Hameed HMA, Zhang T. Microbiol Spectr. 2025 Apr;13(4):e0228924. doi: 10.1128/spectrum.02289-24. Epub 2025 Feb 26. PubMed |
| A conserved phage phosphoesterase enables evasion of bacterial antiviral immunity. Li J, Song Y, Guo X, He ZG. EMBO Rep. 2025 Jul;26(14):3594-3613. doi: 10.1038/s44319-025-00488-4. Epub 2025 May 29. PubMed |
| CRISPRi knockdown of mycobacterial tkt gene potentiates the anti-mycobacterial activity of phyto-compounds from selected medicinal plants. Matotoka MM, Mashabela GT, Masoko P. BMC Complement Med Ther. 2025 Jul 4;25(1):240. doi: 10.1186/s12906-025-04987-8. PubMed |
| A CRISPR/Cas9-based system using dual-sgRNAs for efficient gene deletion in Mycobacterium abscessus. Li L, Hu Y, Wang D, Li X, Bao S, Deng T, Wang Q. Front Microbiol. 2025 Jul 9;16:1608274. doi: 10.3389/fmicb.2025.1608274. eCollection 2025. PubMed |
| The pH gradient contributes to persistence in Mycobacterium tuberculosis. Sherman D, Eldesouky H, Adams K, Brache J, Aguila L, Garcia M, Xing E, Li PK. Res Sq [Preprint]. 2025 Sep 15:rs.3.rs-7466214. doi: 10.21203/rs.3.rs-7466214/v1. PubMed |
| Repression of mab_1999 impairs growth and alters cellular morphology of Mycobacterium abscessus. Ilmi AFN, Kaewsapsak P, Rotcheewaphan S. BMC Microbiol. 2025 Oct 2;25(1):599. doi: 10.1186/s12866-025-04319-3. PubMed |
| The impact of CwlM depletion on the susceptibility of Mycobacterium smegmatis to anti-tuberculosis drugs. Yang S, Ren Y, Wu Y, Li X, Liu X, Deng G. PLoS One. 2025 Oct 24;20(10):e0334937. doi: 10.1371/journal.pone.0334937. eCollection 2025. PubMed |
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