Ubiquitin WT Citations (15)

Originally described in: A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination.
Brzovic PS, Lissounov A, Christensen DE, Hoyt DW, Klevit RE Mol Cell. 2006 Mar 17. 21(6):873-80. PubMed Journal

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Articles Citing Ubiquitin WT

Articles
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by the platinum-based anticancer drugs. Atipairin A, Canyuk B, Ratanaphan A. Breast Cancer Res Treat. 2011 Feb;126(1):203-9. doi: 10.1007/s10549-010-1182-7. Epub 2010 Sep 29. PubMed
Substitution of aspartic acid with glutamic acid at position 67 of the BRCA1 RING domain retains ubiquitin ligase activity and zinc(II) binding with a reduced transition temperature. Atipairin A, Canyuk B, Ratanaphan A. J Biol Inorg Chem. 2011 Feb;16(2):217-26. doi: 10.1007/s00775-010-0718-y. Epub 2010 Oct 22. PubMed
Motion of a disordered polypeptide chain as studied by paramagnetic relaxation enhancements, 15N relaxation, and molecular dynamics simulations: how fast is segmental diffusion in denatured ubiquitin? Xue Y, Skrynnikov NR. J Am Chem Soc. 2011 Sep 21;133(37):14614-28. doi: 10.1021/ja201605c. Epub 2011 Aug 24. PubMed
In Vitro Enhanced Sensitivity to Cisplatin in D67Y BRCA1 RING Domain Protein. Atipairin A, Ratanaphan A. Breast Cancer (Auckl). 2011;5:201-8. doi: 10.4137/BCBCR.S8184. Epub 2011 Sep 25. PubMed
New crystal form of human ubiquitin in the presence of magnesium. Camara-Artigas A, Plaza-Garrido M, Martinez-Rodriguez S, Bacarizo J. Acta Crystallogr F Struct Biol Commun. 2016 Jan 1;72(Pt 1):29-35. doi: 10.1107/S2053230X15023390. Epub 2016 Jan 1. PubMed
Lethal Factor Domain-Mediated Delivery of Nurr1 Transcription Factor Enhances Tyrosine Hydroxylase Activity and Protects from Neurotoxin-Induced Degeneration of Dopaminergic Cells. Paliga D, Raudzus F, Leppla SH, Heumann R, Neumann S. Mol Neurobiol. 2018 Aug 18. pii: 10.1007/s12035-018-1311-6. doi: 10.1007/s12035-018-1311-6. PubMed
A Chemical Strategy for Protease Substrate Profiling. Griswold AR, Cifani P, Rao SD, Axelrod AJ, Miele MM, Hendrickson RC, Kentsis A, Bachovchin DA. Cell Chem Biol. 2019 Jun 20;26(6):901-907.e6. doi: 10.1016/j.chembiol.2019.03.007. Epub 2019 Apr 18. PubMed
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-kappaB via phosphoinosotide remodeling of endosomes. Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D. Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2. PubMed
Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. Schellenberg MJ, Appel CD, Riccio AA, Butler LR, Krahn JM, Liebermann JA, Cortes-Ledesma F, Williams RS. Nucleic Acids Res. 2020 Jun 19;48(11):6310-6325. doi: 10.1093/nar/gkaa318. PubMed
Characterization of Small-Molecule-Induced Changes in Parkinson's-Related Trafficking via the Nedd4 Ubiquitin Signaling Cascade. Hatstat AK, Ahrendt HD, Foster MW, Mayne L, Moseley MA, Englander SW, McCafferty DG. Cell Chem Biol. 2021 Jan 21;28(1):14-25.e9. doi: 10.1016/j.chembiol.2020.10.008. Epub 2020 Nov 10. PubMed
Generation of Monoubiquitin and K63-Linked Polyubiquitin Chains for Protein Interaction Studies. Anoh R, Burke KA, Schmelyun DP, Lombardi PM. Methods Mol Biol. 2022;2444:271-282. doi: 10.1007/978-1-0716-2063-2_16. PubMed
The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP. Umano A, Fang K, Qu Z, Scaglione JB, Altinok S, Treadway CJ, Wick ET, Paulakonis E, Karunanayake C, Chou S, Bardakjian TM, Gonzalez-Alegre P, Page RC, Schisler JC, Brown NG, Yan D, Scaglione KM. J Biol Chem. 2022 May;298(5):101899. doi: 10.1016/j.jbc.2022.101899. Epub 2022 Apr 7. PubMed
Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain. Reiter KH, Zelter A, Janowska MK, Riffle M, Shulman N, MacLean BX, Tamura K, Chambers MC, MacCoss MJ, Davis TN, Guttman M, Brzovic PS, Klevit RE. Structure. 2022 Sep 1;30(9):1269-1284.e6. doi: 10.1016/j.str.2022.05.017. Epub 2022 Jun 17. PubMed
Structural insight into the DNMT1 reaction cycle by cryo-electron microscopy. De I, Weidenhausen J, Concha N, Muller CW. PLoS One. 2024 Sep 3;19(9):e0307850. doi: 10.1371/journal.pone.0307850. eCollection 2024. PubMed
Protocol for evaluating the E3 ligase activity of BRCA1-BARD1 and its variants by nucleosomal histone ubiquitylation. Fitzgerald O, Wu B, Wang M, Maqbool R, Li W, Zhao W. STAR Protoc. 2024 Sep 20;5(3):103294. doi: 10.1016/j.xpro.2024.103294. Epub 2024 Sep 6. PubMed

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