pLentiRNAGuide_002 - hU6-RfxCas13d-DR-BsmBI-EFS-Puro-WPRE Citations (6)
Originally described in: Massively parallel Cas13 screens reveal principles for guide RNA design.Wessels HH, Mendez-Mancilla A, Guo X, Legut M, Daniloski Z, Sanjana NE Nat Biotechnol. 2020 Jun;38(6):722-727. doi: 10.1038/s41587-020-0456-9. Epub 2020 Mar 16. PubMed Journal
Articles Citing pLentiRNAGuide_002 - hU6-RfxCas13d-DR-BsmBI-EFS-Puro-WPRE
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| RNA m(6)A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability. Xiong F, Wang R, Lee JH, Li S, Chen SF, Liao Z, Hasani LA, Nguyen PT, Zhu X, Krakowiak J, Lee DF, Han L, Tsai KL, Liu Y, Li W. Cell Res. 2021 Aug;31(8):861-885. doi: 10.1038/s41422-021-00515-8. Epub 2021 Jun 9. PubMed |
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Lee JH, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen PT, Moroz-Omori EV, Shao J, Zhu X, Bolt MJ, Wu H, Singh PK, Bi M, Shi CJ, Jamal N, Li G, Mistry R, Jung SY, Tsai KL, Ferreon JC, Stossi F, Caflisch A, Liu Z, Mancini MA, Li W.
Mol Cell. 2021 Aug 19;81(16):3368-3385.e9. doi: 10.1016/j.molcel.2021.07.024. Epub 2021 Aug 9.
PubMed
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| METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma. Vaid R, Thombare K, Mendez A, Burgos-Panadero R, Djos A, Jachimowicz D, Lundberg KI, Bartenhagen C, Kumar N, Tummler C, Sihlbom C, Fransson S, Johnsen JI, Kogner P, Martinsson T, Fischer M, Mondal T. Nucleic Acids Res. 2024 Jan 5:gkad1242. doi: 10.1093/nar/gkad1242. PubMed |
A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells.
Tieu V, Sotillo E, Bjelajac JR, Chen C, Malipatlolla M, Guerrero JA, Xu P, Quinn PJ, Fisher C, Klysz D, Mackall CL, Qi LS.
Cell. 2024 Feb 29;187(5):1278-1295.e20. doi: 10.1016/j.cell.2024.01.035. Epub 2024 Feb 21.
PubMed
Associated Plasmids |
| An Isoform-Specific RUNX1C-BTG2 Axis Governs AML Quiescence and Chemoresistance. Han C, Zhang Z, Crosse EI, Sajedi S, Lu B, Wang X, Karma S, Kostich M, Rajendran SH, Udy DB, Chen S, Arnuk A, Lawal AE, Koenig KR, McKenna M, Reville PK, Abbas HA, Abdel-Wahab O, Miura P, Bradley RK, Wang E. Blood Cancer Discov. 2025 Sep 3;6(5):464-483. doi: 10.1158/2643-3230.BCD-24-0327. PubMed |
| Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox. Schertzer MD, Stirn A, Isaev K, Pereira L, Park SH, Das A, Real A, Jeffery ED, Harbison C, Wessels HH, Sheynkman GM, Sanjana NE, Knowles DA. Nat Commun. 2025 Jul 29;16(1):6948. doi: 10.1038/s41467-025-62066-5. PubMed |
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