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TETv4 Citations (8)

Originally described in: Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS Cell. 2021 Apr 7. pii: S0092-8674(21)00353-6. doi: 10.1016/j.cell.2021.03.025. PubMed Journal

Articles Citing TETv4

Articles
CRISPR-based DNA methylation editing of NNT rescues the cisplatin resistance of lung cancer cells by reducing autophagy. Xu C, Jiang S, Ma X, Jiang Z, Pan Y, Li X, Zhang L, Zhou H, Chen S, Xing X, Chen L, Fu W, Wang Q, Chen W, Li D. Arch Toxicol. 2023 Feb;97(2):441-456. doi: 10.1007/s00204-022-03404-0. Epub 2022 Nov 6. PubMed
Srd5a1 is Differentially Regulated and Methylated During Prepubertal Development in the Ovary and Hypothalamus. Bar-Sadeh B, Pnueli L, Keestra S, Bentley GR, Melamed P. J Endocr Soc. 2023 Aug 16;7(10):bvad108. doi: 10.1210/jendso/bvad108. eCollection 2023 Aug 28. PubMed
Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing. Rohm D, Black JB, McCutcheon SR, Barrera A, Morone DJ, Nuttle X, de Esch CE, Tai DJC, Talkowski ME, Iglesias N, Gersbach CA. bioRxiv [Preprint]. 2024 Mar 4:2024.03.03.583177. doi: 10.1101/2024.03.03.583177. PubMed
Extended replicative lifespan of primary resting T cells by CRISPR/dCas9-based epigenetic modifiers and transcriptional activators. Huang S, Lau CH, Tin C, Lam RHW. Cell Mol Life Sci. 2024 Sep 17;81(1):407. doi: 10.1007/s00018-024-05415-9. PubMed
Activation of the imprinted Prader-Willi syndrome locus by CRISPR-based epigenome editing. Rohm D, Black JB, McCutcheon SR, Barrera A, Berry SS, Morone DJ, Nuttle X, de Esch CE, Tai DJC, Talkowski ME, Iglesias N, Gersbach CA. Cell Genom. 2025 Feb 12;5(2):100770. doi: 10.1016/j.xgen.2025.100770. PubMed

Associated Plasmids
The ZBTB24-CDCA7-HELLS axis suppresses the totipotent 2C-like reprogramming by maintaining Dux methylation and repression. Guo D, Du Z, Liu Y, Lin M, Lu Y, Hardikar S, Xue Y, Zhang J, Chen T, Dan J. Nucleic Acids Res. 2025 Apr 10;53(7):gkaf302. doi: 10.1093/nar/gkaf302. PubMed
Removal of promoter CpG methylation by epigenome editing reverses HBG silencing. Bell HW, Feng R, Shah M, Yao Y, Douglas J, Doerfler PA, Mayuranathan T, O'Dea MF, Li Y, Wang YD, Zhang J, Mackay JP, Cheng Y, Quinlan KGR, Weiss MJ, Crossley M. Nat Commun. 2025 Jul 27;16(1):6919. doi: 10.1038/s41467-025-62177-z. PubMed
Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins. Xu D, Besselink S, Ramadoss GN, Dierks PH, Lubin JP, Pattali RK, Brim JI, Christenson AE, Colias PJ, Ornelas IJ, Nguyen CD, Chasins SE, Conklin BR, Nunez JK. Nat Commun. 2025 Aug 26;16(1):7948. doi: 10.1038/s41467-025-63167-x. PubMed

Associated Plasmids

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