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pBABE-neo-hTERT Citations (24)

Originally described in: Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.
Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8.
PubMed Journal

Articles Citing pBABE-neo-hTERT

Articles
Novel isolation and biochemical characterization of immortalized fibroblasts for tissue engineering vocal fold lamina propria. Chen X, Thibeault SL. Tissue Eng Part C Methods. 2009 Jun;15(2):201-12. doi: 10.1089/ten.tec.2008.0390. PubMed
Establishment of immortalized human periodontal ligament cells derived from deciduous teeth. Hasegawa T, Chosa N, Asakawa T, Yoshimura Y, Ishisaki A, Tanaka M. Int J Mol Med. 2010 Nov;26(5):701-5. PubMed
Hippo pathway effector Yap is an ovarian cancer oncogene. Hall CA, Wang R, Miao J, Oliva E, Shen X, Wheeler T, Hilsenbeck SG, Orsulic S, Goode S. Cancer Res. 2010 Nov 1. 70(21):8517-25. PubMed
Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas. Karst AM, Levanon K, Duraisamy S, Liu JF, Hirsch MS, Hecht JL, Drapkin R. Gynecol Oncol. 2011 Oct;123(1):5-12. doi: 10.1016/j.ygyno.2011.05.021. Epub 2011 Jun 17. PubMed
Primary culture and immortalization of human fallopian tube secretory epithelial cells. Karst AM, Drapkin R. Nat Protoc. 2012 Sep;7(9):1755-64. doi: 10.1038/nprot.2012.097. Epub 2012 Aug 30. PubMed
Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells. Ramunas J, Yakubov E, Brady JJ, Corbel SY, Holbrook C, Brandt M, Stein J, Santiago JG, Cooke JP, Blau HM. FASEB J. 2015 May;29(5):1930-9. doi: 10.1096/fj.14-259531. Epub 2015 Jan 22. PubMed
Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Fridriksdottir AJ, Kim J, Villadsen R, Klitgaard MC, Hopkinson BM, Petersen OW, Ronnov-Jessen L. Nat Commun. 2015 Nov 13;6:8786. doi: 10.1038/ncomms9786. PubMed
Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system. Garcia-Mesa Y, Jay TR, Checkley MA, Luttge B, Dobrowolski C, Valadkhan S, Landreth GE, Karn J, Alvarez-Carbonell D. J Neurovirol. 2016 Nov 21. PubMed
Bovine trophectoderm cells induced from bovine fibroblasts with induced pluripotent stem cell reprogramming factors. Talbot NC, Sparks WO, Phillips CE, Ealy AD, Powell AM, Caperna TJ, Garrett WM, Donovan DM, Blomberg LA. Mol Reprod Dev. 2017 Jun;84(6):468-485. doi: 10.1002/mrd.22797. Epub 2017 Apr 12. PubMed
Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors. Mahfouz N, Tahtouh R, Alaaeddine N, El Hajj J, Sarkis R, Hachem R, Raad I, Hilal G. PLoS One. 2017 Jun 8;12(6):e0179202. doi: 10.1371/journal.pone.0179202. eCollection 2017. PubMed
Adipose tissue stem cell-derived hepatic progenies as an in vitro model for genotoxicity testing. Tomc J, Kolosa K, Zegura B, Kamensek U, Breznik B, Turnsek TL, Filipic M. Arch Toxicol. 2018 May;92(5):1893-1903. doi: 10.1007/s00204-018-2190-3. Epub 2018 Mar 16. PubMed
Immortalization of common marmoset monkey fibroblasts by piggyBac transposition of hTERT. Petkov S, Kahland T, Shomroni O, Lingner T, Salinas G, Fuchs S, Debowski K, Behr R. PLoS One. 2018 Sep 27;13(9):e0204580. doi: 10.1371/journal.pone.0204580. eCollection 2018. PubMed
Epigenetic ageing is distinct from senescence-mediated ageing and is not prevented by telomerase expression. Kabacik S, Horvath S, Cohen H, Raj K. Aging (Albany NY). 2018 Oct 17;10(10):2800-2815. doi: 10.18632/aging.101588. PubMed
Assessment of different strategies for scalable production and proliferation of human myoblasts. Chua MJ, Yildirim ED, Tan JE, Chua YB, Low SC, Ding SLS, Li CW, Jiang Z, Teh BT, Yu K, Shyh-Chang N. Cell Prolif. 2019 May;52(3):e12602. doi: 10.1111/cpr.12602. Epub 2019 Mar 19. PubMed
Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen-125 secretion in ovarian carcinoma. Antoun S, Atallah D, Tahtouh R, Assaf MD, Moubarak M, Ayoub EN, Chahine G, Hilal G. Oncol Lett. 2020 Feb;19(2):1338-1350. doi: 10.3892/ol.2019.11233. Epub 2019 Dec 20. PubMed
Immortalization of Mesenchymal Stromal Cells by TERT Affects Adenosine Metabolism and Impairs their Immunosuppressive Capacity. Beckenkamp LR, da Fontoura DMS, Korb VG, de Campos RP, Onzi GR, Iser IC, Bertoni APS, Sevigny J, Lenz G, Wink MR. Stem Cell Rev Rep. 2020 Aug;16(4):776-791. doi: 10.1007/s12015-020-09986-5. PubMed
ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients. Apelt K, White SM, Kim HS, Yeo JE, Kragten A, Wondergem AP, Rooimans MA, Gonzalez-Prieto R, Wiegant WW, Lunke S, Flanagan D, Pantaleo S, Quinlan C, Hardikar W, van Attikum H, Vertegaal ACO, Wilson BT, Wolthuis RMF, Scharer OD, Luijsterburg MS. J Exp Med. 2021 Mar 1;218(3). pii: 211590. doi: 10.1084/jem.20200622. PubMed
Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma. Alexander JI, Vendramini-Costa DB, Francescone R, Luong T, Franco-Barraza J, Shah N, Gardiner JC, Nicolas E, Raghavan KS, Cukierman E. Sci Rep. 2021 Feb 15;11(1):3802. doi: 10.1038/s41598-021-82937-3. PubMed
Hypoxia-Inducible Factor 1alpha (HIF1alpha) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis. Wise LM, Xi Y, Purdy JG. mBio. 2021 Mar 23;12(2). pii: mBio.02956-20. doi: 10.1128/mBio.02956-20. PubMed
Establishment of Down's syndrome periodontal ligament cells by transfection with SV40T-Ag and hTERT. Asakawa T, Yamada A, Kugino M, Hasegawa T, Yoshimura K, Sasa K, Kinoshita M, Nitta M, Nagata K, Sugiyama T, Kamijo R, Funatsu T. Hum Cell. 2022 Jan;35(1):379-383. doi: 10.1007/s13577-021-00621-0. Epub 2021 Sep 29. PubMed
Development of a biologically immortalized equine stem cell line. Nino-Fong R, Esparza Gonzalez BP, Rodriguez-Lecompte JC, Montelpare W, McDuffee L. Can J Vet Res. 2021 Oct;85(4):293-301. PubMed
Irisin Stimulates the Release of CXCL1 From Differentiating Human Subcutaneous and Deep-Neck Derived Adipocytes via Upregulation of NFkappaB Pathway. Shaw A, Toth BB, Kiraly R, Arianti R, Csomos I, Poliska S, Vamos A, Korponay-Szabo IR, Bacso Z, Gyory F, Fesus L, Kristof E. Front Cell Dev Biol. 2021 Oct 11;9:737872. doi: 10.3389/fcell.2021.737872. eCollection 2021. PubMed
Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars. Martinez-Zamudio RI, Stefa A, Nabuco Leva Ferreira Freitas JA, Vasilopoulos T, Simpson M, Dore G, Roux PF, Galan MA, Chokshi RJ, Bischof O, Herbig U. Cell Genom. 2023 Apr 5;3(4):100293. doi: 10.1016/j.xgen.2023.100293. eCollection 2023 Apr 12. PubMed
Cancer associated fibroblasts serve as an ovarian cancer stem cell niche through noncanonical Wnt5a signaling. Fang Y, Xiao X, Wang J, Dasari S, Pepin D, Nephew KP, Zamarin D, Mitra AK. NPJ Precis Oncol. 2024 Jan 8;8(1):7. doi: 10.1038/s41698-023-00495-5. PubMed

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