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pLKO.1 puro shRNA beta-catenin Citations (20)

Plasmid Article: Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.
Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA Cancer Res. 2008 May 15. 68(10):3645-54.
PubMed Journal

Articles Citing pLKO.1 puro shRNA beta-catenin

A Wnt/beta-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes. Ma B, van Blitterswijk CA, Karperien M. Arthritis Rheum. 2012 Aug;64(8):2589-600. doi: 10.1002/art.34425. PubMed
Mechanism of beta-catenin-mediated transcriptional regulation of epidermal growth factor receptor expression in glycogen synthase kinase 3 beta-inactivated prostate cancer cells. Guturi KK, Mandal T, Chatterjee A, Sarkar M, Bhattacharya S, Chatterjee U, Ghosh MK. J Biol Chem. 2012 May 25;287(22):18287-96. doi: 10.1074/jbc.M111.324798. Epub 2012 Apr 5. PubMed
gamma-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of beta-catenin. Morgan RG, Pearn L, Liddiard K, Pumford SL, Burnett AK, Tonks A, Darley RL. Leukemia. 2013 Feb;27(2):336-43. doi: 10.1038/leu.2012.221. Epub 2012 Aug 3. PubMed
WNT/beta-catenin signaling inhibits CBP-mediated RelA acetylation and expression of proinflammatory NF-kappaB target genes. Ma B, Fey M, Hottiger MO. J Cell Sci. 2015 Jul 15;128(14):2430-6. doi: 10.1242/jcs.168542. Epub 2015 May 28. PubMed
Critical role of Wnt/beta-catenin signaling in driving epithelial ovarian cancer platinum resistance. Nagaraj AB, Joseph P, Kovalenko O, Singh S, Armstrong A, Redline R, Resnick K, Zanotti K, Waggoner S, DiFeo A. Oncotarget. 2015 Sep 15;6(27):23720-34. PubMed
SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression. Santos JC, Carrasco-Garcia E, Garcia-Puga M, Aldaz P, Montes M, Fernandez-Reyes M, de Oliveira CC, Lawrie CH, Arauzo-Bravo MJ, Ribeiro ML, Matheu A. Cancer Res. 2016 Nov 15;76(22):6735-6746. doi: 10.1158/0008-5472.CAN-16-1120. Epub 2016 Aug 28. PubMed
Both bulk and cancer stem cell subpopulations in triple-negative breast cancer are susceptible to Wnt, HDAC, and ERalpha coinhibition. Sulaiman A, Sulaiman B, Khouri L, McGarry S, Nessim C, Arnaout A, Li X, Addison C, Dimitroulakos J, Wang L. FEBS Lett. 2016 Dec;590(24):4606-4616. doi: 10.1002/1873-3468.12496. Epub 2016 Dec 9. PubMed
beta-Catenin Knockdown Affects Mitochondrial Biogenesis and Lipid Metabolism in Breast Cancer Cells. Vergara D, Stanca E, Guerra F, Priore P, Gaballo A, Franck J, Simeone P, Trerotola M, De Domenico S, Fournier I, Bucci C, Salzet M, Giudetti AM, Maffia M. Front Physiol. 2017 Jul 27;8:544. doi: 10.3389/fphys.2017.00544. eCollection 2017. PubMed
Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1. Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Lipchick BC, Kolesnikova M, Jowdy P, Polechetti A, Mahpour A, Ross J, Wawrzyniak JA, Yun DH, Paragh G, Kozlova NI, Berman AE, Wang J, Liu S, Nemeth MJ, Nikiforov MA. Cell Rep. 2017 Sep 19;20(12):2820-2832. doi: 10.1016/j.celrep.2017.08.057. PubMed
Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment. Nagaraj AB, Wang QQ, Joseph P, Zheng C, Chen Y, Kovalenko O, Singh S, Armstrong A, Resnick K, Zanotti K, Waggoner S, Xu R, DiFeo A. Oncogene. 2018 Jan 18;37(3):403-414. doi: 10.1038/onc.2017.328. Epub 2017 Oct 2. PubMed
APC downregulated 1 inhibits breast cancer cell invasion by inhibiting the canonical WNT signaling pathway. Cho SG. Oncol Lett. 2017 Oct;14(4):4845-4852. doi: 10.3892/ol.2017.6801. Epub 2017 Aug 23. PubMed
Ectopic Expression of Snail and Twist in Ph+ Leukemia Cells Upregulates CD44 Expression and Alters Their Differentiation Potential. Kidan N, Khamaisie H, Ruimi N, Roitman S, Eshel E, Dally N, Ruthardt M, Mahajna J. J Cancer. 2017 Oct 23;8(19):3952-3968. doi: 10.7150/jca.19633. eCollection 2017. PubMed
Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states. Sulaiman A, McGarry S, Li L, Jia D, Ooi S, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Gadde S, Li X, Wang L. Mol Oncol. 2018 Apr;12(4):423-440. doi: 10.1002/1878-0261.12167. Epub 2018 Feb 21. PubMed
FOXQ1 controls the induced differentiation of melanocytic cells. Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Kolesnikova M, Roll MV, Jowdy P, Wolff DW, Polechetti A, Yun DH, Lipchick BC, Paul LM, Wrazen B, Moparthy K, Mudambi S, Morozevich GE, Georgieva SG, Wang J, Shafirstein G, Liu S, Kandel ES, Berman AE, Box NF, Paragh G, Nikiforov MA. Cell Death Differ. 2018 Jun;25(6):1040-1049. doi: 10.1038/s41418-018-0066-y. Epub 2018 Feb 20. PubMed
Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells. Kim JY, Lee JS, Hwang HS, Lee DR, Park CY, Jung SJ, You YR, Kim DS, Kim DW. Exp Mol Med. 2018 Apr 13;50(4):24. doi: 10.1038/s12276-018-0044-y. PubMed
beta-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors. You C, Zhang S, Sun Y, Zhang S, Tang G, Tang F, Liu X, Xiao Y, Zhang J, Gong Y, Xie C. Int J Oncol. 2018 Nov;53(5):2258-2268. doi: 10.3892/ijo.2018.4529. Epub 2018 Aug 21. PubMed
RNA helicase p68 deploys beta-catenin in regulating RelA/p65 gene expression: implications in colon cancer. Khare V, Tabassum S, Chatterjee U, Chatterjee S, Ghosh MK. J Exp Clin Cancer Res. 2019 Jul 27;38(1):330. doi: 10.1186/s13046-019-1304-y. PubMed
Essentiality of CTNNB1 in Malignant Transformation of Human Embryonic Stem Cells under Long-Term Suboptimal Conditions. Liu J, Zeng S, Wang Y, Yu J, Ouyang Q, Hu L, Zhou D, Lin G, Sun Y. Stem Cells Int. 2020 Sep 24;2020:5823676. doi: 10.1155/2020/5823676. eCollection 2020. PubMed
miR-637 Prevents Glioblastoma Progression by Interrupting ZEB2/WNT/beta-catenin Cascades. Wang W, Zhao Z, Han S, Wu D. Cell Mol Neurobiol. 2021 May 28. pii: 10.1007/s10571-021-01107-1. doi: 10.1007/s10571-021-01107-1. PubMed
Genome-scale CRISPR-Cas9 screen of Wnt/beta-catenin signaling identifies therapeutic targets for colorectal cancer. Wan C, Mahara S, Sun C, Doan A, Chua HK, Xu D, Bian J, Li Y, Zhu D, Sooraj D, Cierpicki T, Grembecka J, Firestein R. Sci Adv. 2021 May 19;7(21). pii: 7/21/eabf2567. doi: 10.1126/sciadv.abf2567. Print 2021 May. PubMed

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