pLenti PGK Blast V5-LUC (w528-1) Citations (22)
Originally described in: A versatile viral system for expression and depletion of proteins in mammalian cells.Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD. PLoS One. 2009 Aug 6;4(8):e6529. PubMed Journal
Articles Citing pLenti PGK Blast V5-LUC (w528-1)
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| Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma. Gil del Alcazar CR, Hardebeck MC, Mukherjee B, Tomimatsu N, Gao X, Yan J, Xie XJ, Bachoo R, Li L, Habib AA, Burma S. Clin Cancer Res. 2014 Mar 1;20(5):1235-48. doi: 10.1158/1078-0432.CCR-13-1607. Epub 2013 Dec 23. PubMed |
| Talin1 phosphorylation activates beta1 integrins: a novel mechanism to promote prostate cancer bone metastasis. Jin JK, Tien PC, Cheng CJ, Song JH, Huang C, Lin SH, Gallick GE. Oncogene. 2015 Apr 2;34(14):1811-21. doi: 10.1038/onc.2014.116. Epub 2014 May 5. PubMed |
| O-GlcNAc modification of transcription factor Sp1 mediates hyperglycemia-induced VEGF-A upregulation in retinal cells. Donovan K, Alekseev O, Qi X, Cho W, Azizkhan-Clifford J. Invest Ophthalmol Vis Sci. 2014 Oct 28;55(12):7862-73. doi: 10.1167/iovs.14-14048. PubMed |
| Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer. Rodrigues LU, Rider L, Nieto C, Romero L, Karimpour-Fard A, Loda M, Lucia MS, Wu M, Shi L, Cimic A, Sirintrapun SJ, Nolley R, Pac C, Chen H, Peehl DM, Xu J, Liu W, Costello JC, Cramer SD. Cancer Res. 2015 Mar 15;75(6):1021-34. doi: 10.1158/0008-5472.CAN-14-1596. PubMed |
Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.
Bajikar SS, Wang CC, Borten MA, Pereira EJ, Atkins KA, Janes KA.
Dev Cell. 2017 Nov 20;43(4):418-435.e13. doi: 10.1016/j.devcel.2017.10.027.
PubMed
Associated Plasmids |
| Increased type III TGF-beta receptor shedding decreases tumorigenesis through induction of epithelial-to-mesenchymal transition. Huang JJ, Corona AL, Dunn BP, Cai EM, Prakken JN, Blobe GC. Oncogene. 2019 May;38(18):3402-3414. doi: 10.1038/s41388-018-0672-7. Epub 2019 Jan 14. PubMed |
| Phomaketide A Inhibits Lymphangiogenesis in Human Lymphatic Endothelial Cells. Tai HC, Lee TH, Tang CH, Chen LP, Chen WC, Lee MS, Chen PC, Lin CY, Chi CW, Chen YJ, Lai CT, Chen SS, Liao KW, Lee CH, Wang SW. Mar Drugs. 2019 Apr 6;17(4). pii: md17040215. doi: 10.3390/md17040215. PubMed |
| The transcription factor FOXM1 regulates the balance between proliferation and aberrant differentiation in head and neck squamous cell carcinoma. Roh V, Hiou-Feige A, Misetic V, Rivals JP, Sponarova J, Teh MT, Ferreira Lopes S, Truan Z, Mermod M, Monnier Y, Hess J, Tolstonog GV, Simon C. J Pathol. 2020 Jan;250(1):107-119. doi: 10.1002/path.5342. Epub 2019 Dec 3. PubMed |
| Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas. Chung C, Sweha SR, Pratt D, Tamrazi B, Panwalkar P, Banda A, Bayliss J, Hawes D, Yang F, Lee HJ, Shan M, Cieslik M, Qin T, Werner CK, Wahl DR, Lyssiotis CA, Bian Z, Shotwell JB, Yadav VN, Koschmann C, Chinnaiyan AM, Bluml S, Judkins AR, Venneti S. Cancer Cell. 2020 Sep 14;38(3):334-349.e9. doi: 10.1016/j.ccell.2020.07.008. Epub 2020 Aug 13. PubMed |
| Y box binding protein 1 inhibition as a targeted therapy for ovarian cancer. Tailor D, Resendez A, Garcia-Marques FJ, Pandrala M, Going CC, Bermudez A, Kumar V, Rafat M, Nambiar DK, Honkala A, Le QT, Sledge GW, Graves E, Pitteri SJ, Malhotra SV. Cell Chem Biol. 2021 Aug 19;28(8):1206-1220.e6. doi: 10.1016/j.chembiol.2021.02.014. Epub 2021 Mar 12. PubMed |
| VIVA1: a more invasive subclone of MDA-MB-134VI invasive lobular carcinoma cells with increased metastatic potential in xenograft models. Allen V, Coulombe J, Zhao H, Kreps LM, Cook DP, Pryce B, Clemons M, Vanderhyden BC, Gray DA, Addison CL. Br J Cancer. 2022 Jul;127(1):56-68. doi: 10.1038/s41416-022-01778-7. Epub 2022 Mar 22. PubMed |
| Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism. Monteiro C, Miarka L, Perea-Garcia M, Priego N, Garcia-Gomez P, Alvaro-Espinosa L, de Pablos-Aragoneses A, Yebra N, Retana D, Baena P, Fustero-Torre C, Grana-Castro O, Troule K, Caleiras E, Tezanos P, Muela P, Cintado E, Trejo JL, Sepulveda JM, Gonzalez-Leon P, Jimenez-Roldan L, Moreno LM, Esteban O, Perez-Nunez A, Hernandez-Lain A, Mazarico Gallego J, Ferrer I, Suarez R, Garrido-Martin EM, Paz-Ares L, Dalmasso C, Cohen-Jonathan Moyal E, Siegfried A, Hegarty A, Keelan S, Vareslija D, Young LS, Mohme M, Goy Y, Wikman H, Fernandez-Alen J, Blasco G, Alcazar L, Cabanuz C, Grivennikov SI, Ianus A, Shemesh N, Faria CC, Lee R, Lorigan P, Le Rhun E, Weller M, Soffietti R, Bertero L, Ricardi U, Bosch-Barrera J, Sais E, Teixidor E, Hernandez-Martinez A, Calvo A, Aristu J, Martin SM, Gonzalez A, Adler O, Erez N, Valiente M. Nat Med. 2022 Apr;28(4):752-765. doi: 10.1038/s41591-022-01749-8. Epub 2022 Apr 11. PubMed |
| Stress Granules Determine the Development of Obesity-Associated Pancreatic Cancer. Fonteneau G, Redding A, Hoag-Lee H, Sim ES, Heinrich S, Gaida MM, Grabocka E. Cancer Discov. 2022 Aug 5;12(8):1984-2005. doi: 10.1158/2159-8290.CD-21-1672. PubMed |
| Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus. Taha Z, Crupi MJF, Alluqmani N, Fareez F, Ng K, Sobh J, Lee E, Chen A, Thomson M, Spinelli MM, Ilkow CS, Bell JC, Arulanandam R, Diallo JS. Front Immunol. 2023 Apr 19;14:1181014. doi: 10.3389/fimmu.2023.1181014. eCollection 2023. PubMed |
| The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability. Ravn-Boess N, Roy N, Hattori T, Bready D, Donaldson H, Lawson C, Lapierre C, Korman A, Rodrick T, Liu E, Frenster JD, Stephan G, Wilcox J, Corrado AD, Cai J, Ronnen R, Wang S, Haddock S, Sabio Ortiz J, Mishkit O, Khodadadi-Jamayran A, Tsirigos A, Fenyo D, Zagzag D, Drube J, Hoffmann C, Perna F, Jones DR, Possemato R, Koide A, Koide S, Park CY, Placantonakis DG. Cell Rep. 2023 Nov 28;42(11):113374. doi: 10.1016/j.celrep.2023.113374. Epub 2023 Nov 8. PubMed |
| Alternations in inflammatory macrophage niche drive phenotypic and functional plasticity of Kupffer cells. Huang HY, Chen YZ, Zhao C, Zheng XN, Yu K, Yue JX, Ju HQ, Shi YX, Tian L. Nat Commun. 2024 Oct 29;15(1):9337. doi: 10.1038/s41467-024-53659-7. PubMed |
| Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate. Chen X, Augello MA, Liu D, Lin K, Hakansson A, Sjostrom M, Khani F, Deonarine LD, Liu Y, Travascio-Green J, Wu J, Chan UI, Owiredu J, Loda M, Feng FY, Robinson BD, Davicioni E, Sboner A, Barbieri CE. Nat Commun. 2024 Dec 13;15(1):10675. doi: 10.1038/s41467-024-53734-z. PubMed |
| PCSK5(M452I) is a recessive hypomorph exclusive to MCF10DCIS.com cells. Marohl T, Atkins KA, Wang L, Janes KA. bioRxiv [Preprint]. 2025 Mar 7:2025.03.03.641323. doi: 10.1101/2025.03.03.641323. PubMed |
| Lysine-arginine imbalance overcomes therapeutic tolerance governed by the transcription factor E3-lysosome axis in glioblastoma. Jing Y, Kobayashi M, Shoulkamy MI, Zhou M, Thi Vu H, Arakawa H, Sabit H, Iwabuchi S, Quang Vu C, Kasahara A, Ueno M, Tadokoro Y, Kurayoshi K, Chen X, Yan Y, Arai S, Hashimoto S, Soga T, Todo T, Nakada M, Hirao A. Nat Commun. 2025 Apr 1;16(1):2876. doi: 10.1038/s41467-025-56946-z. PubMed |
| Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis. Dang D, Deogharkar A, McKolay J, Smith KS, Panwalkar P, Hoffman S, Tian W, Ji S, Azambuja AP, Natarajan SK, Lum J, Bayliss J, Manzeck K, Sweha SR, Hamanishi E, Pun M, Patel D, Rau S, Animasahun O, Achreja A, Ogrodzinski MP, Diessl J, Cotter J, Hawes D, Yang F, Doherty R, Franson AT, Hanaford AR, Eberhart CG, Raabe EH, Orr BA, Wechsler-Reya RJ, Chen B, Lyssiotis CA, Shah YM, Lunt SY, Banerjee R, Judkins AR, Prensner JR, Koschmann C, Waszak SM, Nagrath D, Simoes-Costa M, Northcott PA, Venneti S. Cancer Cell. 2025 Jun 9;43(6):1159-1174.e8. doi: 10.1016/j.ccell.2025.04.013. Epub 2025 May 15. PubMed |
| L1CAM signaling through planar cell polarity generates SOX2 (+) metastatic progenitors in lung adenocarcinoma. Park JS, Kaygusuz Y, Kenum C, He L, Gatie MI, Zhuang X, Sharma R, Chaligne R, Bhanot UK, Koche RP, Tammela T, Hadjantonakis AK, Rudin CM, Massague J. bioRxiv [Preprint]. 2025 Aug 23:2025.08.22.671773. doi: 10.1101/2025.08.22.671773. PubMed |
PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells.
Marohl T, Atkins KA, Wang L, Janes KA.
Mol Cancer Res. 2025 Oct 28. doi: 10.1158/1541-7786.MCR-25-0211.
PubMed
Associated Plasmids |
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