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pDONR223-JAK2 Citations (4)

Originally described in: COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
PubMed Journal

Articles Citing pDONR223-JAK2

JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. Wang S, Liang K, Hu Q, Li P, Song J, Yang Y, Yao J, Mangala LS, Li C, Yang W, Park PK, Hawke DH, Zhou J, Zhou Y, Xia W, Hung MC, Marks JR, Gallick GE, Lopez-Berestein G, Flores ER, Sood AK, Huang S, Yu D, Yang L, Lin C. J Clin Invest. 2017 Dec 1;127(12):4498-4515. doi: 10.1172/JCI91553. Epub 2017 Nov 13. PubMed
Mutations in the IFNgamma-JAK-STAT Pathway Causing Resistance to Immune Checkpoint Inhibitors in Melanoma Increase Sensitivity to Oncolytic Virus Treatment. Nguyen TT, Ramsay L, Ahanfeshar-Adams M, Lajoie M, Schadendorf D, Alain T, Watson IR. Clin Cancer Res. 2021 Jun 15;27(12):3432-3442. doi: 10.1158/1078-0432.CCR-20-3365. Epub 2021 Feb 16. PubMed
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer. Wang W, Tang YA, Xiao Q, Lee WC, Cheng B, Niu Z, Oguz G, Feng M, Lee PL, Li B, Yang ZH, Chen YF, Lan P, Wu XJ, Yu Q. Nat Commun. 2021 Jul 21;12(1):4441. doi: 10.1038/s41467-021-24687-4. PubMed
A novel germline hyperactivating JAK2 mutation L604F. Dvoracek L, Markova J, Holoubek A, Grebenova D, Kundrat D, Kuzelova K, Schwarz J. Ann Hematol. 2023 Oct;102(10):2725-2734. doi: 10.1007/s00277-023-05423-y. Epub 2023 Aug 28. PubMed

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