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3XFlag DVL2 (WT) Citations (16)

Originally described in: Regulation of planar cell polarity by Smurf ubiquitin ligases.
Narimatsu M, Bose R, Pye M, Zhang L, Miller B, Ching P, Sakuma R, Luga V, Roncari L, Attisano L, Wrana JL Cell. 2009 Apr 17. 137(2):295-307.
PubMed Journal

Articles Citing 3XFlag DVL2 (WT)

A mutation in FRIZZLED2 impairs Wnt signaling and causes autosomal dominant omodysplasia. Saal HM, Prows CA, Guerreiro I, Donlin M, Knudson L, Sund KL, Chang CF, Brugmann SA, Stottmann RW. Hum Mol Genet. 2015 Jun 15;24(12):3399-409. doi: 10.1093/hmg/ddv088. Epub 2015 Mar 10. PubMed
An IkappaB Kinase-Regulated Feedforward Circuit Prolongs Inflammation. Perez JM, Chirieleison SM, Abbott DW. Cell Rep. 2015 Jul 28;12(4):537-44. doi: 10.1016/j.celrep.2015.06.050. Epub 2015 Jul 16. PubMed
The polycystin complex mediates Wnt/Ca(2+) signalling. Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L. Nat Cell Biol. 2016 Jul;18(7):752-64. doi: 10.1038/ncb3363. Epub 2016 May 23. PubMed
Inhibition of disheveled-2 resensitizes cisplatin-resistant lung cancer cells through down-regulating Wnt/beta-catenin signaling. Luo K, Gu X, Liu J, Zeng G, Peng L, Huang H, Jiang M, Yang P, Li M, Yang Y, Wang Y, Peng Q, Zhu L, Zhang K. Exp Cell Res. 2016 Sep 10;347(1):105-13. doi: 10.1016/j.yexcr.2016.07.014. Epub 2016 Jul 16. PubMed
Apigenin-induced lysosomal degradation of beta-catenin in Wnt/beta-catenin signaling. Lin CM, Chen HH, Lin CA, Wu HC, Sheu JJ, Chen HJ. Sci Rep. 2017 Mar 23;7(1):372. doi: 10.1038/s41598-017-00409-z. PubMed
Statins do not inhibit the FGFR signaling in chondrocytes. Fafilek B, Hampl M, Ricankova N, Vesela I, Balek L, Kunova Bosakova M, Gudernova I, Varecha M, Buchtova M, Krejci P. Osteoarthritis Cartilage. 2017 Jun 3. pii: S1063-4584(17)31024-5. doi: 10.1016/j.joca.2017.05.014. PubMed
The tyrosine Y2502.39 in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled. Strakova K, Matricon P, Yokota C, Arthofer E, Bernatik O, Rodriguez D, Arenas E, Carlsson J, Bryja V, Schulte G. Cell Signal. 2017 Jun 29;38:85-96. doi: 10.1016/j.cellsig.2017.06.018. PubMed
Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization. Strakova K, Kowalski-Jahn M, Gybel T, Valnohova J, Dhople VM, Harnos J, Bernatik O, Ganji RS, Zdrahal Z, Mulder J, Lindskog C, Bryja V, Schulte G. J Biol Chem. 2018 Nov 30;293(48):18477-18493. doi: 10.1074/jbc.RA118.004656. Epub 2018 Oct 11. PubMed
RASSF10 suppresses lung cancer proliferation and invasion by decreasing the level of phosphorylated LRP6. Han X, Dong Q, Wu J, Luo Y, Rong X, Han Q, Zheng X, Wang E. Mol Carcinog. 2019 Jul;58(7):1168-1180. doi: 10.1002/mc.23000. Epub 2019 Mar 4. PubMed
Pleiotropic tumor suppressor functions of WWOX antagonize metastasis. Khawaled S, Nigita G, Distefano R, Oster S, Suh SS, Smith Y, Khalaileh A, Peng Y, Croce CM, Geiger T, Seewaldt VL, Aqeilan RI. Signal Transduct Target Ther. 2020 Apr 17;5(1):43. doi: 10.1038/s41392-020-0136-8. PubMed
FOXM1/DVL2/Snail axis drives metastasis and chemoresistance of colorectal cancer. Yang Y, Jiang H, Li W, Chen L, Zhu W, Xian Y, Han Z, Yin L, Liu Y, Wang Y, Pan K, Zhang K. Aging (Albany NY). 2020 Dec 3;12(23):24424-24440. doi: 10.18632/aging.202300. Epub 2020 Dec 3. PubMed
USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling. Giebel N, de Jaime-Soguero A, Garcia Del Arco A, Landry JJM, Tietje M, Villacorta L, Benes V, Fernandez-Saiz V, Acebron SP. EMBO Rep. 2021 May 5;22(5):e51415. doi: 10.15252/embr.202051415. Epub 2021 Mar 30. PubMed
Roles of individual human Dishevelled paralogs in the Wnt signalling pathways. Paclikova P, Radaszkiewicz TW, Potesil D, Harnos J, Zdrahal Z, Bryja V. Cell Signal. 2021 Sep;85:110058. doi: 10.1016/j.cellsig.2021.110058. Epub 2021 May 31. PubMed
RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. Radaszkiewicz T, Noskova M, Gomoryova K, Vondalova Blanarova O, Radaszkiewicz KA, Pickova M, Vichova R, Gybel T, Kaiser K, Demkova L, Kucerova L, Barta T, Potesil D, Zdrahal Z, Soucek K, Bryja V. Elife. 2021 Oct 27;10. pii: 65759. doi: 10.7554/eLife.65759. PubMed
DIX domain containing 1 (DIXDC1) modulates VEGFR2 level in vasculatures to regulate embryonic and postnatal retina angiogenesis. Kim Y, Kim DY, Zhang H, Bae CR, Seong D, Kim Y, Song J, Kim YM, Kwon YG. BMC Biol. 2022 Feb 10;20(1):41. doi: 10.1186/s12915-022-01240-3. PubMed
Heterozygous variants in the DVL2 interaction region of DACT1 cause CAKUT and features of Townes-Brocks syndrome 2. Christians A, Kesdiren E, Hennies I, Hofmann A, Trowe MO, Brand F, Martens H, Gjerstad AC, Gucev Z, Zirngibl M, Geffers R, Seeman T, Billing H, Bjerre A, Tasic V, Kispert A, Ure B, Haffner D, Dingemann J, Weber RG. Hum Genet. 2023 Jan;142(1):73-88. doi: 10.1007/s00439-022-02481-6. Epub 2022 Sep 6. PubMed

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