Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

pLKO.1-blast Citations (34)

Plasmid Article: A molecular network for de novo generation of the apical surface and lumen.
Bryant DM, Datta A, Rodriguez-Fraticelli AE, Peranen J, Martin-Belmonte F, Mostov KE Nat Cell Biol. 2010 Oct 3. ():.
PubMed Journal

Articles Citing pLKO.1-blast

Articles
PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells. Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y, Nakayama M, Hashimoto S, Nakamura T, Sugasawa K, Kojima N, Takada T, Okano M, Seki Y. Development. 2014 Jan;141(2):269-80. doi: 10.1242/dev.099622. Epub 2013 Dec 11. PubMed
Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations. Larrue C, Saland E, Vergez F, Serhan N, Delabesse E, Mansat-De Mas V, Hospital MA, Tamburini J, Manenti S, Sarry JE, Recher C. Mol Cancer Ther. 2015 Oct;14(10):2364-73. doi: 10.1158/1535-7163.MCT-15-0163. Epub 2015 Jul 23. PubMed
Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells. Larrue C, Saland E, Boutzen H, Vergez F, David M, Joffre C, Hospital MA, Tamburini J, Delabesse E, Manenti S, Sarry JE, Recher C. Blood. 2015 Aug 18. pii: blood-2015-05-646497. PubMed
Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF. Nat Commun. 2016 May 3;7:11246. doi: 10.1038/ncomms11246. PubMed
An RNA matchmaker protein regulates the activity of the long noncoding RNA HOTAIR. Meredith EK, Balas MM, Sindy K, Haislop K, Johnson AM. RNA. 2016 Jul;22(7):995-1010. doi: 10.1261/rna.055830.115. Epub 2016 May 4. PubMed
Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-beta-dependent mechanisms. Shi X, Mihaylova VT, Kuruvilla L, Chen F, Viviano S, Baldassarre M, Sperandio D, Martinez R, Yue P, Bates JG, Breckenridge DG, Schlessinger J, Turk BE, Calderwood DA. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4558-66. doi: 10.1073/pnas.1608319113. Epub 2016 Jul 18. PubMed
Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia. Lam SS, Ho ES, He BL, Wong WW, Cher CY, Ng NK, Man CH, Gill H, Cheung AM, Ip HW, So CC, Tamburini J, So CW, Ho DN, Au CH, Chan TL, Ma ES, Liang R, Kwong YL, Leung AY. Sci Transl Med. 2016 Oct 5;8(359):359ra129. PubMed
SIKs control osteocyte responses to parathyroid hormone. Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O'Meara MJ, Govea N, Beqo B, Nishimori S, Nagano K, Brooks DJ, Martins JS, Corbin B, Anselmo A, Sadreyev R, Wu JY, Sakamoto K, Foretz M, Xavier RJ, Baron R, Bouxsein ML, Gardella TJ, Divieti-Pajevic P, Gray NS, Kronenberg HM. Nat Commun. 2016 Oct 19;7:13176. doi: 10.1038/ncomms13176. PubMed
PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency. Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, Kawaguchi M, Kashida H, Nakajima A, Tachibana M, Seki Y. Stem Cell Reports. 2016 Dec 13;7(6):1072-1086. doi: 10.1016/j.stemcr.2016.10.007. Epub 2016 Nov 17. PubMed
G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer. Yim CY, Bikorimana E, Khan E, Warzecha JM, Shin L, Rodriguez J, Dmitrovsky E, Freemantle SJ, Spinella MJ. Cell Cycle. 2017;16(21):2146-2155. doi: 10.1080/15384101.2017.1371884. Epub 2017 Sep 14. PubMed
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1. Feng YX, Jin DX, Sokol ES, Reinhardt F, Miller DH, Gupta PB. Nat Commun. 2017 Oct 20;8(1):1079. doi: 10.1038/s41467-017-01052-y. PubMed
Hoxa9 and Hoxa10 induce CML myeloid blast crisis development through activation of Myb expression. Negi V, Vishwakarma BA, Chu S, Oakley K, Han Y, Bhatia R, Du Y. Oncotarget. 2017 Oct 24;8(58):98853-98864. doi: 10.18632/oncotarget.22008. eCollection 2017 Nov 17. PubMed
The concerted roles of FANCM and Rad52 in the protection of common fragile sites. Wang H, Li S, Oaks J, Ren J, Li L, Wu X. Nat Commun. 2018 Jul 18;9(1):2791. doi: 10.1038/s41467-018-05066-y. PubMed
RAP2 mediates mechanoresponses of the Hippo pathway. Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. Nature. 2018 Aug;560(7720):655-660. doi: 10.1038/s41586-018-0444-0. Epub 2018 Aug 22. PubMed
Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG Jr. Cell. 2018 Sep 20;175(1):101-116.e25. doi: 10.1016/j.cell.2018.08.038. Epub 2018 Sep 13. PubMed
Role of PDGF receptor-alpha during human cytomegalovirus entry into fibroblasts. Wu K, Oberstein A, Wang W, Shenk T. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9889-E9898. doi: 10.1073/pnas.1806305115. Epub 2018 Oct 1. PubMed
Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma. Mohamed AD, Shah N, Hettmer S, Vargesson N, Wackerhage H. Sci Rep. 2018 Oct 23;8(1):15674. doi: 10.1038/s41598-018-33852-7. PubMed
DNA polymerase theta (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse. Wang Z, Song Y, Li S, Kurian S, Xiang R, Chiba T, Wu X. J Biol Chem. 2019 Mar 15;294(11):3909-3919. doi: 10.1074/jbc.RA118.005188. Epub 2019 Jan 17. PubMed
The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer. Rampias T, Karagiannis D, Avgeris M, Polyzos A, Kokkalis A, Kanaki Z, Kousidou E, Tzetis M, Kanavakis E, Stravodimos K, Manola KN, Pantelias GE, Scorilas A, Klinakis A. EMBO Rep. 2019 Mar;20(3). pii: embr.201846821. doi: 10.15252/embr.201846821. Epub 2019 Jan 21. PubMed
L1 drives IFN in senescent cells and promotes age-associated inflammation. De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beausejour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9. Epub 2019 Feb 6. PubMed
ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures. Li S, Lu H, Wang Z, Hu Q, Wang H, Xiang R, Chiba T, Wu X. iScience. 2019 Jun 28;16:63-78. doi: 10.1016/j.isci.2019.05.017. Epub 2019 May 16. PubMed
DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction. Marivin A, Garcia-Marcos M. Mol Biol Cell. 2019 Jul 22;30(16):1900-1910. doi: 10.1091/mbc.E19-02-0091. Epub 2019 Jul 3. PubMed
Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis. Pringle ES, Robinson CA, McCormick C. J Virol. 2019 Oct 15;93(21). pii: JVI.00854-19. doi: 10.1128/JVI.00854-19. Print 2019 Nov 1. PubMed
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Gomes AP, Ilter D, Low V, Rosenzweig A, Shen ZJ, Schild T, Rivas MA, Er EE, McNally DR, Mutvei AP, Han J, Ou YH, Cavaliere P, Mullarky E, Nagiec M, Shin S, Yoon SO, Dephoure N, Massague J, Melnick AM, Cantley LC, Tyler JK, Blenis J. Cancer Cell. 2019 Oct 14;36(4):402-417.e13. doi: 10.1016/j.ccell.2019.08.006. Epub 2019 Sep 26. PubMed
Kaposi's Sarcoma-Associated Herpesvirus ORF66 Is Essential for Late Gene Expression and Virus Production via Interaction with ORF34. Watanabe T, Nishimura M, Izumi T, Kuriyama K, Iwaisako Y, Hosokawa K, Takaori-Kondo A, Fujimuro M. J Virol. 2020 Jan 6;94(2). pii: JVI.01300-19. doi: 10.1128/JVI.01300-19. Print 2020 Jan 6. PubMed
Histone methyltransferases EHMT1 and EHMT2 (GLP/G9A) maintain PARP inhibitor resistance in high-grade serous ovarian carcinoma. Watson ZL, Yamamoto TM, McMellen A, Kim H, Hughes CJ, Wheeler LJ, Post MD, Behbakht K, Bitler BG. Clin Epigenetics. 2019 Nov 27;11(1):165. doi: 10.1186/s13148-019-0758-2. PubMed
Dynein-mediated nuclear translocation of yes-associated protein through microtubule acetylation controls fibroblast activation. You E, Ko P, Jeong J, Keum S, Kim JW, Seo YJ, Song WK, Rhee S. Cell Mol Life Sci. 2020 Jan 7. pii: 10.1007/s00018-019-03412-x. doi: 10.1007/s00018-019-03412-x. PubMed
An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation. Raffeiner P, Hart JR, Garcia-Caballero D, Bar-Peled L, Weinberg MS, Vogt PK. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6571-6579. doi: 10.1073/pnas.1921786117. Epub 2020 Mar 10. PubMed
PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability. Che N, Ng KY, Wong TL, Tong M, Kau PW, Chan LH, Lee TK, Huen MS, Yun JP, Ma S. Cancer Lett. 2021 Mar 31;501:247-262. doi: 10.1016/j.canlet.2020.11.002. Epub 2020 Nov 11. PubMed
Xpo7 negatively regulates Hedgehog signaling by exporting Gli2 from the nucleus. Markiewicz L, Uspienski T, Baran B, Niedziolka SM, Niewiadomski P. Cell Signal. 2021 Apr;80:109907. doi: 10.1016/j.cellsig.2020.109907. Epub 2020 Dec 28. PubMed
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors. Patel PS, Abraham KJ, Guturi KKN, Halaby MJ, Khan Z, Palomero L, Ho B, Duan S, St-Germain J, Algouneh A, Mateo F, El Ghamrasni S, Barbour H, Barnes DR, Beesley J, Sanchez O, Berman HK, Brown GW, Affar EB, Chenevix-Trench G, Antoniou AC, Arrowsmith CH, Raught B, Pujana MA, Mekhail K, Hakem A, Hakem R. J Clin Invest. 2021 Feb 1;131(3). pii: 140105. doi: 10.1172/JCI140105. PubMed
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J. Elife. 2021 May 26;10. pii: 67624. doi: 10.7554/eLife.67624. PubMed
NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA. Yamamoto Y, Chino H, Tsukamoto S, Ode KL, Ueda HR, Mizushima N. Nat Commun. 2021 Jun 2;12(1):3292. doi: 10.1038/s41467-021-23599-7. PubMed
Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress. Ko P, Choi JH, Song S, Keum S, Jeong J, Hwang YE, Kim JW, Rhee S. Int J Mol Sci. 2021 Jun 2;22(11). pii: ijms22116018. doi: 10.3390/ijms22116018. PubMed

If you have published an article using this plasmid, please email us at [email protected] to have your article added to this page.