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pOPTN-EGFP Citations (14)

Originally described in: Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types.
Park BC, Shen X, Samaraweera M, Yue BY Am J Pathol. 2006 Dec . 169(6):1976-89.
PubMed Journal

Articles Citing pOPTN-EGFP

Inducible turnover of optineurin regulates T cell activation. Montecalvo A, Watkins SC, Orange J, Kane LP. Mol Immunol. 2017 May;85:9-17. doi: 10.1016/j.molimm.2017.01.027. Epub 2017 Feb 11. PubMed
Inverted recruitment of autophagy proteins to the Plasmodium berghei parasitophorous vacuole membrane. Schmuckli-Maurer J, Reber V, Wacker R, Bindschedler A, Zakher A, Heussler VT. PLoS One. 2017 Aug 25;12(8):e0183797. doi: 10.1371/journal.pone.0183797. eCollection 2017. PubMed
ANGPTL8 negatively regulates NF-kappaB activation by facilitating selective autophagic degradation of IKKgamma. Zhang Y, Guo X, Yan W, Chen Y, Ke M, Cheng C, Zhu X, Xue W, Zhou Q, Zheng L, Wang S, Wu B, Liu X, Ma L, Huang L, Huang K. Nat Commun. 2017 Dec 18;8(1):2164. doi: 10.1038/s41467-017-02355-w. PubMed
The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau). Xu Y, Zhang S, Zheng H. Autophagy. 2019 Apr;15(4):583-598. doi: 10.1080/15548627.2018.1532258. Epub 2018 Oct 16. PubMed
Imaging the Dynamics of Mitophagy in Live Cells. Moore AS, Holzbaur ELF. Methods Mol Biol. 2019;1880:601-610. doi: 10.1007/978-1-4939-8873-0_39. PubMed
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10. Wauters F, Cornelissen T, Imberechts D, Martin S, Koentjoro B, Sue C, Vangheluwe P, Vandenberghe W. Autophagy. 2019 Apr 4:1-20. doi: 10.1080/15548627.2019.1603548. PubMed
Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway. Bowling JL, Skolfield MC, Riley WA, Nolin AP, Wolf LC, Nelson DE. BMC Mol Cell Biol. 2019 Aug 14;20(1):33. doi: 10.1186/s12860-019-0220-5. PubMed
Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity. Ye J, Cheung J, Gerbino V, Ahlsen G, Zimanyi C, Hirsh D, Maniatis T. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24517-24526. doi: 10.1073/pnas.1915732116. Epub 2019 Nov 20. PubMed
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy. Imberechts D, Kinnart I, Wauters F, Terbeek J, Manders L, Wierda K, Eggermont K, Madeiro RF, Sue C, Verfaillie C, Vandenberghe W. Brain. 2022 Dec 19;145(12):4368-4384. doi: 10.1093/brain/awac313. PubMed
Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics. Cazzaro S, Fang C, Khan H, Witas R, Kee TR, Woo JA, Kang DE. Front Aging Neurosci. 2022 Aug 25;14:933979. doi: 10.3389/fnagi.2022.933979. eCollection 2022. PubMed
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy. Kocaturk NM, Peker N, Eberhart K, Akkoc Y, Deveci G, Dengjel J, Gozuacik D. Cell Death Dis. 2022 Nov 10;13(11):947. doi: 10.1038/s41419-022-05339-x. PubMed
Enhanced Levels of Peroxisome-Derived H(2)O(2) Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells. Li H, Lismont C, Costa CF, Hussein MAF, Baes M, Fransen M. Antioxidants (Basel). 2023 Mar 2;12(3):613. doi: 10.3390/antiox12030613. PubMed
Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion. Minami Y, Hoshino A, Higuchi Y, Hamaguchi M, Kaneko Y, Kirita Y, Taminishi S, Nishiji T, Taruno A, Fukui M, Arany Z, Matoba S. Nat Commun. 2023 Jul 13;14(1):4084. doi: 10.1038/s41467-023-39404-6. PubMed

Associated Plasmids

Role of ALS-associated OPTN-K489E mutation in neuronal cell-death regulation. Mishra D, Narain P, Dave U, Gomes J. Mol Cell Neurosci. 2023 Dec;127:103904. doi: 10.1016/j.mcn.2023.103904. Epub 2023 Oct 31. PubMed

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