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Tet-O-FUW-Myt1l Citations (19)

Originally described in: Direct conversion of fibroblasts to functional neurons by defined factors.
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof TC, Wernig M Nature. 2010 Feb 25. 463(7284):1035-41.
PubMed Journal

Articles Citing Tet-O-FUW-Myt1l

Articles
Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells. Adler AF, Grigsby CL, Kulangara K, Wang H, Yasuda R, Leong KW. Mol Ther Nucleic Acids. 2012 Jul 10;1:e32. doi: 10.1038/mtna.2012.25. PubMed
From the Cover: Neutralization of terminal differentiation in gliomagenesis. Hu J, Ho AL, Yuan L, Hu B, Hua S, Hwang SS, Zhang J, Hu T, Zheng H, Gan B, Wu G, Wang YA, Chin L, DePinho RA. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14520-7. doi: 10.1073/pnas.1308610110. Epub 2013 Aug 5. PubMed
The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. Kulangara K, Adler AF, Wang H, Chellappan M, Hammett E, Yasuda R, Leong KW. Biomaterials. 2014 Jul;35(20):5327-36. doi: 10.1016/j.biomaterials.2014.03.034. Epub 2014 Apr 4. PubMed
Transdifferentiation of mouse fibroblasts and hepatocytes to functional neurons. Marro S, Yang N. Methods Mol Biol. 2014;1150:237-46. doi: 10.1007/978-1-4939-0512-6_16. PubMed
A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification. Chakraborty S, Ji H, Kabadi AM, Gersbach CA, Christoforou N, Leong KW. Stem Cell Reports. 2014 Dec 9;3(6):940-7. doi: 10.1016/j.stemcr.2014.09.013. Epub 2014 Oct 23. PubMed

Associated Plasmids

Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells. Fishman VS, Shnayder TA, Orishchenko KE, Bader M, Alenina N, Serov OL. Cell Cycle. 2015;14(8):1188-96. doi: 10.1080/15384101.2015.1012875. PubMed
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, Karakhanyan A, Pang Z, Fu XD. Nat Neurosci. 2016 Jun;19(6):807-15. doi: 10.1038/nn.4297. Epub 2016 Apr 25. PubMed
Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks. Miskinyte G, Devaraju K, Gronning Hansen M, Monni E, Tornero D, Woods NB, Bengzon J, Ahlenius H, Lindvall O, Kokaia Z. Stem Cell Res Ther. 2017 Sep 29;8(1):207. doi: 10.1186/s13287-017-0658-3. PubMed
Analysis of transcriptional activity by the Myt1 and Myt1l transcription factors. Manukyan A, Kowalczyk I, Melhuish TA, Lemiesz A, Wotton D. J Cell Biochem. 2018 Jun;119(6):4644-4655. doi: 10.1002/jcb.26636. Epub 2018 Mar 9. PubMed
Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression. Melhuish TA, Kowalczyk I, Manukyan A, Zhang Y, Shah A, Abounader R, Wotton D. Biochim Biophys Acta Gene Regul Mech. 2018 Nov;1861(11):983-995. doi: 10.1016/j.bbagrm.2018.10.005. Epub 2018 Oct 10. PubMed
Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion. Matsuda T, Irie T, Katsurabayashi S, Hayashi Y, Nagai T, Hamazaki N, Adefuin AMD, Miura F, Ito T, Kimura H, Shirahige K, Takeda T, Iwasaki K, Imamura T, Nakashima K. Neuron. 2019 Feb 6;101(3):472-485.e7. doi: 10.1016/j.neuron.2018.12.010. Epub 2019 Jan 9. PubMed
Tox4 modulates cell fate reprogramming. Vanheer L, Song J, De Geest N, Janiszewski A, Talon I, Provenzano C, Oh T, Chappell J, Pasque V. J Cell Sci. 2019 Oct 22;132(20). pii: jcs.232223. doi: 10.1242/jcs.232223. PubMed
Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, Srinivasan R, Li X, Devarajan K, Prelot L, Ang CE, Shibuya Y, Benayoun BA, Chang ALS, Wernig M, Wysocka J, Longaker MT, Snyder MP, Brunet A. Nature. 2019 Oct;574(7779):553-558. doi: 10.1038/s41586-019-1658-5. Epub 2019 Oct 23. PubMed
Human cell transformation by combined lineage conversion and oncogene expression. Sahu B, Pihlajamaa P, Zhang K, Palin K, Ahonen S, Cervera A, Ristimaki A, Aaltonen LA, Hautaniemi S, Taipale J. Oncogene. 2021 Sep;40(36):5533-5547. doi: 10.1038/s41388-021-01940-0. Epub 2021 Jul 23. PubMed
Isolation and Neuronal Reprogramming of Mouse Embryonic Fibroblasts. Adrian-Segarra JM, Weigel B, Mall M. Methods Mol Biol. 2021;2352:1-12. doi: 10.1007/978-1-0716-1601-7_1. PubMed
Generation of Induced Dopaminergic Neurons from Human Fetal Fibroblasts. Legault EM, Drouin-Ouellet J. Methods Mol Biol. 2021;2352:97-115. doi: 10.1007/978-1-0716-1601-7_7. PubMed
Direct Differentiation of Functional Neurons from Human Pluripotent Stem Cells (hPSCs). Hu R, Zhu X, Yang N. Methods Mol Biol. 2021;2352:117-126. doi: 10.1007/978-1-0716-1601-7_8. PubMed
Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells. Missinato MA, Murphy S, Lynott M, Yu MS, Kervadec A, Chang YL, Kannan S, Loreti M, Lee C, Amatya P, Tanaka H, Huang CT, Puri PL, Kwon C, Adams PD, Qian L, Sacco A, Andersen P, Colas AR. Nat Commun. 2023 Mar 27;14(1):1709. doi: 10.1038/s41467-023-37256-8. PubMed
The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages. Katoku-Kikyo N, Lim S, Yuan C, Koroth J, Nakagawa Y, Bradley EW, Kikyo N. PLoS Biol. 2023 Dec 4;21(12):e3002419. doi: 10.1371/journal.pbio.3002419. eCollection 2023 Dec. PubMed

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