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pcDNA5/FRT-HA-hM4D(Gi) Citations (9)

Originally described in: Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.
Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5163-8. Epub 2007 Mar 2.
PubMed Journal

Articles Citing pcDNA5/FRT-HA-hM4D(Gi)

Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus-->midbrain pathway for feeding behavior. Stachniak TJ, Ghosh A, Sternson SM. Neuron. 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24. PubMed

Associated Plasmids

Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours. Koga K, Kanehisa K, Kohro Y, Shiratori-Hayashi M, Tozaki-Saitoh H, Inoue K, Furue H, Tsuda M. Sci Rep. 2017 Jul 5;7(1):4739. doi: 10.1038/s41598-017-04972-3. PubMed
Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex. Vitali I, Fievre S, Telley L, Oberst P, Bariselli S, Frangeul L, Baumann N, McMahon JJ, Klingler E, Bocchi R, Kiss JZ, Bellone C, Silver DL, Jabaudon D. Cell. 2018 Aug 23;174(5):1264-1276.e15. doi: 10.1016/j.cell.2018.06.036. Epub 2018 Jul 26. PubMed
Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits. Zhou QG, Nemes AD, Lee D, Ro EJ, Zhang J, Nowacki AS, Dymecki SM, Najm IM, Suh H. J Clin Invest. 2019 Jan 2;129(1):310-323. doi: 10.1172/JCI95731. Epub 2018 Dec 3. PubMed
Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics. Weston M, Kaserer T, Wu A, Mouravlev A, Carpenter JC, Snowball A, Knauss S, von Schimmelmann M, During MJ, Lignani G, Schorge S, Young D, Kullmann DM, Lieb A. Sci Adv. 2019 Apr 17;5(4):eaaw1567. doi: 10.1126/sciadv.aaw1567. eCollection 2019 Apr. PubMed
Transient Chemogenetic Inhibition of D1-MSNs in the Dorsal Striatum Enhances Methamphetamine Self-Administration. Oliver RJ, Purohit DC, Kharidia KM, Mandyam CD. Brain Sci. 2019 Nov 19;9(11). pii: brainsci9110330. doi: 10.3390/brainsci9110330. PubMed
Adult-born neurons immature during learning are necessary for remote memory reconsolidation in rats. Lods M, Pacary E, Mazier W, Farrugia F, Mortessagne P, Masachs N, Charrier V, Massa F, Cota D, Ferreira G, Abrous DN, Tronel S. Nat Commun. 2021 Mar 19;12(1):1778. doi: 10.1038/s41467-021-22069-4. PubMed
Chemogenetic silencing of spinal cord-projecting cortical neurons attenuates Abeta fiber-derived neuropathic allodynia in mice. Fujimori K, Sekine M, Watanabe M, Tashima R, Tozaki-Saitoh H, Tsuda M. Neurosci Res. 2022 Aug;181:115-119. doi: 10.1016/j.neures.2022.05.001. Epub 2022 May 6. PubMed
Selective Involvement of a Subset of Spinal Dorsal Horn Neurons Operated by a Prodynorphin Promoter in Abeta Fiber-Mediated Neuropathic Allodynia-Like Behavioral Responses in Rats. Ishibashi T, Yoshikawa Y, Sueto D, Tashima R, Tozaki-Saitoh H, Koga K, Yamaura K, Tsuda M. Front Mol Neurosci. 2022 Jun 23;15:911122. doi: 10.3389/fnmol.2022.911122. eCollection 2022. PubMed

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