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pHR SFFVp BFP-Erk2 Citations (4)

Originally described in: Using optogenetics to interrogate the dynamic control of signal transmission by the ras/erk module.
Toettcher JE, Weiner OD, Lim WA Cell. 2013 Dec 5;155(6):1422-34. doi: 10.1016/j.cell.2013.11.004.
PubMed Journal

Articles Citing pHR SFFVp BFP-Erk2

Quantification of growth factor signaling and pathway cross talk by live-cell imaging. Gross SM, Rotwein P. Am J Physiol Cell Physiol. 2017 Mar 1;312(3):C328-C340. doi: 10.1152/ajpcell.00312.2016. Epub 2017 Jan 18. PubMed
Optogenetic Control of Ras/Erk Signaling Using the Phy-PIF System. Goglia AG, Wilson MZ, DiGiorno DB, Toettcher JE. Methods Mol Biol. 2017;1636:3-20. doi: 10.1007/978-1-4939-7154-1_1. PubMed
Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control. Wilson MZ, Ravindran PT, Lim WA, Toettcher JE. Mol Cell. 2017 Sep 7;67(5):757-769.e5. doi: 10.1016/j.molcel.2017.07.016. Epub 2017 Aug 17. PubMed

Associated Plasmids

Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. Bugaj LJ, Sabnis AJ, Mitchell A, Garbarino JE, Toettcher JE, Bivona TG, Lim WA. Science. 2018 Aug 31;361(6405). pii: 361/6405/eaao3048. doi: 10.1126/science.aao3048. PubMed

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