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pAAV-EF1a-mCherry-IRES-Flpo Citations (20)

Originally described in: Targeting cells with single vectors using multiple-feature Boolean logic.
Fenno LE, Mattis J, Ramakrishnan C, Hyun M, Lee SY, He M, Tucciarone J, Selimbeyoglu A, Berndt A, Grosenick L, Zalocusky KA, Bernstein H, Swanson H, Perry C, Diester I, Boyce FM, Bass CE, Neve R, Huang ZJ, Deisseroth K Nat Methods. 2014 Jul;11(7):763-72. doi: 10.1038/nmeth.2996. Epub 2014 Jun 8.
PubMed Journal

Articles Citing pAAV-EF1a-mCherry-IRES-Flpo

Articles
Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Jung H, Kim SW, Kim M, Hong J, Yu D, Kim JH, Lee Y, Kim S, Woo D, Shin HS, Park BO, Do Heo W. Nat Commun. 2019 Jan 18;10(1):314. doi: 10.1038/s41467-018-08282-8. PubMed

Associated Plasmids

Cocaine- and stress-primed reinstatement of drug-associated memories elicit differential behavioral and frontostriatal circuit activity patterns via recruitment of L-type Ca(2+) channels. Bavley CC, Fetcho RN, Burgdorf CE, Walsh AP, Fischer DK, Hall BS, Sayles NM, Contoreggi NH, Hackett JE, Antigua SA, Babij R, De Marco Garcia NV, Kash TL, Milner TA, Liston C, Rajadhyaksha AM. Mol Psychiatry. 2019 Sep 9. pii: 10.1038/s41380-019-0513-2. doi: 10.1038/s41380-019-0513-2. PubMed
Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening. Marcus DJ, Bedse G, Gaulden AD, Ryan JD, Kondev V, Winters ND, Rosas-Vidal LE, Altemus M, Mackie K, Lee FS, Delpire E, Patel S. Neuron. 2020 Mar 18;105(6):1062-1076.e6. doi: 10.1016/j.neuron.2019.12.024. Epub 2020 Jan 13. PubMed
Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice. Zhang J, Chen X, Eaton M, Wu J, Ma Z, Lai S, Park A, Ahmad TS, Que Z, Lee JH, Xiao T, Li Y, Wang Y, Olivero-Acosta MI, Schaber JA, Jayant K, Yuan C, Huang Z, Lanman NA, Skarnes WC, Yang Y. Cell Rep. 2021 Aug 3;36(5):109495. doi: 10.1016/j.celrep.2021.109495. PubMed
Extinction blunts paraventricular thalamic contributions to heroin relapse. Giannotti G, Gong S, Fayette N, Heinsbroek JA, Orfila JE, Herson PS, Ford CP, Peters J. Cell Rep. 2021 Aug 24;36(8):109605. doi: 10.1016/j.celrep.2021.109605. PubMed
Transcriptional and functional divergence in lateral hypothalamic glutamate neurons projecting to the lateral habenula and ventral tegmental area. Rossi MA, Basiri ML, Liu Y, Hashikawa Y, Hashikawa K, Fenno LE, Kim YS, Ramakrishnan C, Deisseroth K, Stuber GD. Neuron. 2021 Dec 1;109(23):3823-3837.e6. doi: 10.1016/j.neuron.2021.09.020. Epub 2021 Oct 7. PubMed
Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions. Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K. Commun Biol. 2022 Feb 21;5(1):149. doi: 10.1038/s42003-022-03096-3. PubMed

Associated Plasmids

Automated Image Analysis Reveals Different Localization of Synaptic Gephyrin C4 Splice Variants. Liebsch F, Eggersmann FR, Merkler Y, Kloppenburg P, Schwarz G. eNeuro. 2023 Jan 4;10(1):ENEURO.0102-22.2022. doi: 10.1523/ENEURO.0102-22.2022. Print 2023 Jan. PubMed

Associated Plasmids

Lateral septum as a melanocortin downstream site in obesity development. Xu Y, Jiang Z, Li H, Cai J, Jiang Y, Otiz-Guzman J, Xu Y, Arenkiel BR, Tong Q. Cell Rep. 2023 May 30;42(5):112502. doi: 10.1016/j.celrep.2023.112502. Epub 2023 May 11. PubMed

Associated Plasmids

Viral vector-mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome. Fadila S, Beucher B, Dopeso-Reyes IG, Mavashov A, Brusel M, Anderson K, Ismeurt C, Goldberg EM, Ricobaraza A, Hernandez-Alcoceba R, Kremer EJ, Rubinstein M. J Clin Invest. 2023 Jun 15;133(12):e159316. doi: 10.1172/JCI159316. PubMed
Viral vector-mediated transgene delivery with novel recombinase systems for targeting neuronal populations defined by multiple features. Jeong M, Choi JH, Jang H, Sohn DH, Wang Q, Lee J, Yao L, Lee EJ, Fan J, Pratelli M, Wang EH, Snyder CN, Wang XY, Shin S, Gittis AH, Sung TC, Spitzer NC, Lim BK. Neuron. 2024 Jan 3;112(1):56-72.e4. doi: 10.1016/j.neuron.2023.09.038. Epub 2023 Oct 30. PubMed
An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes. Cai J, Jiang Y, Xu Y, Jiang Z, Young C, Li H, Ortiz-Guzman J, Zhuo Y, Li Y, Xu Y, Arenkiel BR, Tong Q. Neuron. 2024 Feb 7;112(3):458-472.e6. doi: 10.1016/j.neuron.2023.11.001. Epub 2023 Dec 5. PubMed
Selective Targeting of a Defined Subpopulation of Corticospinal Neurons using a Novel Klhl14-Cre Mouse Line Enables Molecular and Anatomical Investigations through Development into Maturity. Lustig J, Lammers A, Kaiser J, Patel P, Raghu A, Conner JM, Nguyen P, Azim E, Sahni V. bioRxiv [Preprint]. 2024 Dec 12:2024.12.10.627648. doi: 10.1101/2024.12.10.627648. PubMed
Restoration of excitation/inhibition balance enhances neuronal signal-to-noise ratio and rescues social deficits in autism-associated Scn2a-deficiency. Zhang J, Eaton M, Chen X, Zhao Y, Kant S, Deming BA, Harish K, Nguyen HP, Shu Y, Lai S, Wu J, Que Z, Wettschurack KW, Zhang Z, Xiao T, Halurkar MS, Olivero-Acosta MI, Yoo YE, Lanman NA, Koss WA, Skarnes WC, Yang Y. bioRxiv [Preprint]. 2025 Mar 5:2025.03.04.641498. doi: 10.1101/2025.03.04.641498. PubMed
Striatum supports fast learning but not memory recall. Reinhold K, Iadarola M, Tang S, Chang A, Kuwamoto W, Albanese MA, Sun S, Hakim R, Zimmer J, Wang W, Sabatini BL. Nature. 2025 Jul;643(8071):458-467. doi: 10.1038/s41586-025-08969-1. Epub 2025 May 7. PubMed
Gene therapies alleviate absence epilepsy associated with Scn2a deficiency in DBA/2J mice. Zhang Z, Zhang J, Chen X, Deming BA, Kant S, Mandal P, Kothandaraman H, SanMiguel PJ, Halurkar MS, Abeyaratna AD, Robinson MJ, Zhao Y, Vitko Y, Gaykema RP, Yuan C, Lanman NA, Tegtmeyer MT, Wang D, Gao G, Shi R, Perez-Reyes E, Yang Y. bioRxiv [Preprint]. 2025 Jun 6:2025.06.03.657652. doi: 10.1101/2025.06.03.657652. PubMed
Directed cell-type recruitment during consolidation of a remote memory. Zeidler Z, Yu AL, Seong MP, Hundley R, DeNardo LA. bioRxiv [Preprint]. 2025 Jun 15:2025.06.13.659562. doi: 10.1101/2025.06.13.659562. PubMed
Selective Targeting of a Defined Subpopulation of Corticospinal Neurons Using a Novel Klhl14-Cre Mouse Line Enables Molecular and Anatomical Investigations through Development into Maturity. Lustig J, Lammers A, Kaiser J, Patel P, Raghu A, Conner JM, Nguyen P, Azim E, Sahni V. eNeuro. 2025 Sep 8;12(9):ENEURO.0589-24.2025. doi: 10.1523/ENEURO.0589-24.2025. Print 2025 Sep. PubMed
Synaptic organization and associative learning-related activity of basolateral amygdala interneurons. Baldi R, Muthuswamy S, Yasmin F, Quadir S, Zaidi D, Kwon M, Kandil I, Johnson K, Loomba N, Patel S. Cell Rep. 2025 Oct 28;44(10):116295. doi: 10.1016/j.celrep.2025.116295. Epub 2025 Sep 18. PubMed
Sex-specific role of the 5-HT(2A) receptor in psilocybin-induced extinction of opioid reward. Jaster AM, Hadlock TM, Buzzi B, Maltman JL, Silva GM, Saha S, Koseli E, Pondelick AM, Thakur N, Zhang X, Li G, Ledesma-Corvi S, Moore KN, Peterson HR, Fujita B, Zylko AL, Lewis MR, Poklis JL, Halquist MS, Wolstenholme JT, Selley DE, Hamilton PJ, Lu C, Damaj MI, Gonzalez-Maeso J. Nat Commun. 2025 Nov 20;16(1):10206. doi: 10.1038/s41467-025-64887-w. PubMed

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