pUPRT::DHFR-D Citations (11)

Originally described in: Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9.
Shen B, Brown KM, Lee TD, Sibley LD MBio. 2014 May 13;5(3). pii: e01114-14. doi: 10.1128/mBio.01114-14. PubMed Journal

---

Articles Citing pUPRT::DHFR-D

Articles
Development of CRISPR/Cas9 for Efficient Genome Editing in Toxoplasma gondii. Shen B, Brown K, Long S, Sibley LD. Methods Mol Biol. 2017;1498:79-103. PubMed
Identification of Novel Dense-Granule Proteins in Toxoplasma gondii by Two Proximity-Based Biotinylation Approaches. Pan M, Li M, Li L, Song Y, Hou L, Zhao J, Shen B. J Proteome Res. 2019 Jan 4;18(1):319-330. doi: 10.1021/acs.jproteome.8b00626. Epub 2018 Oct 26. PubMed
The GRA17 Parasitophorous Vacuole Membrane Permeability Pore Contributes to Bradyzoite Viability. Paredes-Santos T, Wang Y, Waldman B, Lourido S, Saeij JP. Front Cell Infect Microbiol. 2019 Sep 12;9:321. doi: 10.3389/fcimb.2019.00321. eCollection 2019. PubMed
In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration. Sangare LO, Olafsson EB, Wang Y, Yang N, Julien L, Camejo A, Pesavento P, Sidik SM, Lourido S, Barragan A, Saeij JPJ. Cell Host Microbe. 2019 Oct 9;26(4):478-492.e8. doi: 10.1016/j.chom.2019.09.008. PubMed
Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNgamma-activated murine macrophages. Wang Y, Sangare LO, Paredes-Santos TC, Hassan MA, Krishnamurthy S, Furuta AM, Markus BM, Lourido S, Saeij JPJ. Nat Commun. 2020 Oct 16;11(1):5258. doi: 10.1038/s41467-020-18991-8. PubMed
Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages. Zhu L, Qi W, Yang G, Yang Y, Wang Y, Zheng L, Fu Y, Cheng X. Cells. 2022 May 12;11(10). pii: cells11101630. doi: 10.3390/cells11101630. PubMed
High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription. Butterworth S, Kordova K, Chandrasekaran S, Thomas KK, Torelli F, Lockyer EJ, Edwards A, Goldstone R, Koshy AA, Treeck M. Cell Host Microbe. 2023 Oct 11;31(10):1748-1762.e8. doi: 10.1016/j.chom.2023.09.003. PubMed
GRA47 and GRA72 are Toxoplasma gondii pore-forming proteins that influence small molecule permeability of the parasitophorous vacuole. Bitew MA, Gaete PS, Swale C, Maru P, Contreras JE, Saeij JPJ. bioRxiv [Preprint]. 2023 Nov 15:2023.11.15.567216. doi: 10.1101/2023.11.15.567216. PubMed
Two Toxoplasma gondii putative pore-forming proteins, GRA47 and GRA72, influence small molecule permeability of the parasitophorous vacuole. Bitew MA, Gaete PS, Swale C, Maru P, Contreras JE, Saeij JPJ. mBio. 2024 Mar 13;15(3):e0308123. doi: 10.1128/mbio.03081-23. Epub 2024 Feb 21. PubMed
Proline dehydrogenase, a rate-limiting catabolic enzyme, affecting the growth and pathogenicity of Toxoplasma gondii tachyzoites by regulating the proline metabolism and mitochondrial function of the parasite. Geng XL, Li JY, Xu HY, Wu JP, Tao DL, Chen JM, Fan YY, Yang X, Song JK, Zhao GH. Parasit Vectors. 2025 Jul 29;18(1):309. doi: 10.1186/s13071-025-06966-x. PubMed
BFD2 mediates inflammation, apoptosis, and pre-anxiety-like behaviors induced by acute Toxoplasma gondii infection. Zhang X, Xu T, Zhu J, Peng H, Wei Z, Cui L, Zuo Q, Liu H, Hu Y, Cao J. PLoS Negl Trop Dis. 2025 Sep 4;19(9):e0013428. doi: 10.1371/journal.pntd.0013428. eCollection 2025 Sep. PubMed

If you have published an article using this material, please email us at to have your article added to this page.