pCMV HA hRb delta CDK Citations (7)
Originally described in: Cyclin D activates the Rb tumor suppressor by mono-phosphorylation.Narasimha AM, Kaulich M, Shapiro GS, Choi YJ, Sicinski P, Dowdy SF Elife. 2014 May 29:e02872. doi: 10.7554/eLife.02872. PubMed Journal
Articles Citing pCMV HA hRb delta CDK
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| p38gamma is essential for cell cycle progression and liver tumorigenesis. Tomas-Loba A, Manieri E, Gonzalez-Teran B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodriguez E, Pintor-Chocano A, Feixas F, Lopez JA, Caballero B, Trakala M, Blanco O, Torres JL, Hernandez-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, Leon M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vazquez J, Malumbres M, Marcos M, Osuna S, Sabio G. Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10. PubMed |
| Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix. Topacio BR, Zatulovskiy E, Cristea S, Xie S, Tambo CS, Rubin SM, Sage J, Koivomagi M, Skotheim JM. Mol Cell. 2019 May 16;74(4):758-770.e4. doi: 10.1016/j.molcel.2019.03.020. Epub 2019 Apr 11. PubMed |
| G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment. Lee Y, Lahens NF, Zhang S, Bedont J, Field JM, Sehgal A. PLoS Biol. 2019 Apr 30;17(4):e3000228. doi: 10.1371/journal.pbio.3000228. eCollection 2019 Apr. PubMed |
| Sox2 Is an Oncogenic Driver of Small-Cell Lung Cancer and Promotes the Classic Neuroendocrine Subtype. Voigt E, Wallenburg M, Wollenzien H, Thompson E, Kumar K, Feiner J, McNally M, Friesen H, Mukherjee M, Afeworki Y, Kareta MS. Mol Cancer Res. 2021 Dec;19(12):2015-2025. doi: 10.1158/1541-7786.MCR-20-1006. Epub 2021 Sep 30. PubMed |
| Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling. Muller L, Keil R, Hatzfeld M. Cell Rep. 2023 Jan 31;42(1):112031. doi: 10.1016/j.celrep.2023.112031. Epub 2023 Jan 22. PubMed |
| MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors' Efficacy in Neuroblastoma Cells. De Rosa P, Severi F, Zadran SK, Russo M, Aloisi S, Rigamonti A, Capranico G, Milazzo G, Perini G. Int J Mol Sci. 2023 Mar 12;24(6):5408. doi: 10.3390/ijms24065408. PubMed |
| Actin-based deformations of the nucleus control mouse multiciliated ependymal cell differentiation. Basso M, Mahuzier A, Ali SK, Marty A, Faucourt M, Lennon-Dumenil AM, Srivastava A, Khoury Damaa M, Bankole A, Meunier A, Yamada A, Plastino J, Spassky N, Delgehyr N. Dev Cell. 2025 Mar 10;60(5):749-761.e5. doi: 10.1016/j.devcel.2024.11.008. Epub 2024 Dec 10. PubMed |
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