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DRD2-Tango Citations (11)

Originally described in: PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.
Kroeze WK, Sassano MF, Huang XP, Lansu K, McCorvy JD, Giguere PM, Sciaky N, Roth BL Nat Struct Mol Biol. 2015 May;22(5):362-9. doi: 10.1038/nsmb.3014. Epub 2015 Apr 20.
PubMed Journal

Articles Citing DRD2-Tango

Articles
Time-gated detection of protein-protein interactions with transcriptional readout. Kim MW, Wang W, Sanchez MI, Coukos R, von Zastrow M, Ting AY. Elife. 2017 Nov 30;6. doi: 10.7554/eLife.30233. PubMed

Associated Plasmids

Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors. Terron-Diaz ME, Wright SJ, Agosto MA, Lichtarge O, Wensel TG. J Biol Chem. 2019 Dec 13;294(50):19279-19291. doi: 10.1074/jbc.RA119.008068. Epub 2019 Nov 1. PubMed
NOX1/NADPH Oxidase Promotes Synaptic Facilitation Induced by Repeated D(2) Receptor Stimulation: Involvement in Behavioral Repetition. Asaoka N, Ibi M, Hatakama H, Nagaoka K, Iwata K, Matsumoto M, Katsuyama M, Kaneko S, Yabe-Nishimura C. J Neurosci. 2021 Mar 24;41(12):2780-2794. doi: 10.1523/JNEUROSCI.2121-20.2021. Epub 2021 Feb 9. PubMed
Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. Arveseth CD, Happ JT, Hedeen DS, Zhu JF, Capener JL, Klatt Shaw D, Deshpande I, Liang J, Xu J, Stubben SL, Nelson IB, Walker MF, Kawakami K, Inoue A, Krogan NJ, Grunwald DJ, Huttenhain R, Manglik A, Myers BR. PLoS Biol. 2021 Apr 22;19(4):e3001191. doi: 10.1371/journal.pbio.3001191. eCollection 2021 Apr. PubMed
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells. Prokop S, Abranyi-Balogh P, Barti B, Vamosi M, Zoldi M, Barna L, Urban GM, Toth AD, Dudok B, Egyed A, Deng H, Leggio GM, Hunyady L, van der Stelt M, Keseru GM, Katona I. Nat Commun. 2021 Nov 11;12(1):6505. doi: 10.1038/s41467-021-26757-z. PubMed
Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled receptors expressed in tumors. Huh E, Gallion J, Agosto MA, Wright SJ, Wensel TG, Lichtarge O. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51). pii: 2113373118. doi: 10.1073/pnas.2113373118. PubMed
Effects of Small Molecule Ligands on ACKR3 Receptors. Hopkins BE, Masuho I, Ren D, Iyamu ID, Lv W, Malik N, Martemyanov KA, Schiltz GE, Miller RJ. Mol Pharmacol. 2022 Sep;102(3):128-138. doi: 10.1124/molpharm.121.000295. Epub 2022 Jul 9. PubMed
Dopamine receptor D2 confers colonization resistance via microbial metabolites. Scott SA, Fu J, Chang PV. Nature. 2024 Apr;628(8006):180-185. doi: 10.1038/s41586-024-07179-5. Epub 2024 Mar 13. PubMed
Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations. Niebrugge N, Trovato O, Praschberger R, Lieb A. Biomedicines. 2024 Dec 28;13(1):46. doi: 10.3390/biomedicines13010046. PubMed
G(o/z)-biased coupling profile of the dopamine D3 receptor. Zanetti L, Franchini L, Saha S, Liao Y, Muntean BS, Orlandi C. bioRxiv [Preprint]. 2025 Aug 12:2025.08.08.668522. doi: 10.1101/2025.08.08.668522. PubMed
Striatal spinophilin enhances dopamine D2 receptor (D2R) interaction with cytosolic proteins to mediate persistent D2R agonist-induced locomotor suppression. Hens B, Smith-Kinneman WR, Doud EH, Baucum AJ 2nd. J Pharmacol Exp Ther. 2026 Jan;393(1):103788. doi: 10.1016/j.jpet.2025.103788. Epub 2025 Dec 4. PubMed

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