pET28-Dnmt3a3L-sc27 Citations (6)
Originally described in: Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity.Siddique AN, Nunna S, Rajavelu A, Zhang Y, Jurkowska RZ, Reinhardt R, Rots MG, Ragozin S, Jurkowski TP, Jeltsch A J Mol Biol. 2013 Feb 8;425(3):479-91. doi: 10.1016/j.jmb.2012.11.038. Epub 2012 Dec 4. PubMed Journal
Articles Citing pET28-Dnmt3a3L-sc27
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| Mutagenesis of the FAE1 genes significantly changes fatty acid composition in seeds of Camelina sativa. Ozseyhan ME, Kang J, Mu X, Lu C. Plant Physiol Biochem. 2018 Feb;123:1-7. doi: 10.1016/j.plaphy.2017.11.021. Epub 2017 Dec 2. PubMed |
| Generation of TALE-Based Designer Epigenome Modifiers. Nitsch S, Mussolino C. Methods Mol Biol. 2018;1767:89-109. doi: 10.1007/978-1-4939-7774-1_4. PubMed |
| Enhanced targeted DNA methylation of the CMV and endogenous promoters with dCas9-DNMT3A3L entails distinct subsequent histone modification changes in CHO cells. Marx N, Dhiman H, Schmieder V, Freire CM, Nguyen LN, Klanert G, Borth N. Metab Eng. 2021 Jul;66:268-282. doi: 10.1016/j.ymben.2021.04.014. Epub 2021 May 16. PubMed |
Discovery of Inhibitors of DNA Methyltransferase 2, an Epitranscriptomic Modulator and Potential Target for Cancer Treatment.
Schwickert M, Fischer TR, Zimmermann RA, Hoba SN, Meidner JL, Weber M, Weber M, Stark MM, Koch J, Jung N, Kersten C, Windbergs M, Lyko F, Helm M, Schirmeister T.
J Med Chem. 2022 Jul 18. doi: 10.1021/acs.jmedchem.2c00388.
PubMed
Associated Plasmids |
Systematic epigenome editing captures the context-dependent instructive function of chromatin modifications.
Policarpi C, Munafo M, Tsagkris S, Carlini V, Hackett JA.
Nat Genet. 2024 Jun;56(6):1168-1180. doi: 10.1038/s41588-024-01706-w. Epub 2024 May 9.
PubMed
Associated Plasmids |
| DNA-encoded library screening uncovers potent DNMT2 inhibitors targeting a cryptic allosteric binding site. Frey AF, Schwan M, Weldert AC, Kadenbach V, Kopp J, Nidoieva Z, Zimmermann RA, Gleue L, Zimmer C, Jorg M, Friedland K, Helm M, Sinning I, Barthels F. iScience. 2025 Aug 5;28(9):113300. doi: 10.1016/j.isci.2025.113300. eCollection 2025 Sep 19. PubMed |
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