pgRNA-CKB Citations (13)
Originally described in: CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR Cell Stem Cell. 2016 Apr 7;18(4):541-53. doi: 10.1016/j.stem.2016.01.022. Epub 2016 Mar 10. PubMed Journal
Articles Citing pgRNA-CKB
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| CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway. Cheng CL, Yang SC, Lai CY, Wang CK, Chang CF, Lin CY, Chen WJ, Lin PY, Wu HC, Ma N, Lu FL, Lu J. Cells. 2020 Jul 16;9(7). pii: cells9071706. doi: 10.3390/cells9071706. PubMed |
CRTC1/MAML2 directs a PGC-1alpha-IGF-1 circuit that confers vulnerability to PPARgamma inhibition.
Musicant AM, Parag-Sharma K, Gong W, Sengupta M, Chatterjee A, Henry EC, Tsai YH, Hayward MC, Sheth S, Betancourt R, Hackman TG, Padilla RJ, Parker JS, Giudice J, Flaveny CA, Hayes DN, Amelio AL.
Cell Rep. 2021 Feb 23;34(8):108768. doi: 10.1016/j.celrep.2021.108768.
PubMed
Associated Plasmids |
Lysyl hydroxylase 2-induced collagen cross-link switching promotes metastasis in head and neck squamous cell carcinomas.
Sato K, Parag-Sharma K, Terajima M, Musicant AM, Murphy RM, Ramsey MR, Hibi H, Yamauchi M, Amelio AL.
Neoplasia. 2021 Jun 6;23(6):594-606. doi: 10.1016/j.neo.2021.05.014.
PubMed
Associated Plasmids |
| Parallel functional assessment of m(6)A sites in human endodermal differentiation with base editor screens. Cheng W, Liu F, Ren Z, Chen W, Chen Y, Liu T, Ma Y, Cao N, Wang J. Nat Commun. 2022 Jan 25;13(1):478. doi: 10.1038/s41467-022-28106-0. PubMed |
| Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation. Anand GM, Megale HC, Murphy SH, Weis T, Lin Z, He Y, Wang X, Liu J, Ramanathan S. Cell. 2023 Feb 2;186(3):497-512.e23. doi: 10.1016/j.cell.2022.12.043. Epub 2023 Jan 18. PubMed |
| Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation. Madrigal P, Deng S, Feng Y, Militi S, Goh KJ, Nibhani R, Grandy R, Osnato A, Ortmann D, Brown S, Pauklin S. Nat Commun. 2023 Jan 25;14(1):405. doi: 10.1038/s41467-023-36116-9. PubMed |
| Loss of TJP1 disrupts gastrulation patterning and increases differentiation toward the germ cell lineage in human pluripotent stem cells. Vasic I, Libby ARG, Maslan A, Bulger EA, Zalazar D, Krakora Compagno MZ, Streets A, Tomoda K, Yamanaka S, McDevitt TC. Dev Cell. 2023 Aug 21;58(16):1477-1488.e5. doi: 10.1016/j.devcel.2023.05.019. Epub 2023 Jun 23. PubMed |
| BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma. Feng Y, Cai L, Pook M, Liu F, Chang CH, Mouti MA, Nibhani R, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Wang C, Hong W, Morgan H, Wang M, Sadayappan S, Jegga AG, Oppermann U, Wang Y, Huang W, Jiang L, Pauklin S. Gastroenterology. 2024 Jan;166(1):139-154. doi: 10.1053/j.gastro.2023.09.021. Epub 2023 Sep 21. PubMed |
| Spatially organized cellular communities form the developing human heart. Farah EN, Hu RK, Kern C, Zhang Q, Lu TY, Ma Q, Tran S, Zhang B, Carlin D, Monell A, Blair AP, Wang Z, Eschbach J, Li B, Destici E, Ren B, Evans SM, Chen S, Zhu Q, Chi NC. Nature. 2024 Mar;627(8005):854-864. doi: 10.1038/s41586-024-07171-z. Epub 2024 Mar 13. PubMed |
| Telomerase is essential for cardiac differentiation and sustained metabolism of human cardiomyocytes. Chatterjee S, Leach-Mehrwald M, Huang CK, Xiao K, Fuchs M, Otto M, Lu D, Dang V, Winkler T, Dunbar CE, Thum T, Bar C. Cell Mol Life Sci. 2024 Apr 24;81(1):196. doi: 10.1007/s00018-024-05239-7. PubMed |
| The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms. Chang CH, Liu F, Militi S, Hester S, Nibhani R, Deng S, Dunford J, Rendek A, Soonawalla Z, Fischer R, Oppermann U, Pauklin S. Nat Commun. 2024 Apr 27;15(1):3580. doi: 10.1038/s41467-024-47680-z. PubMed |
| Single-cell multi-modal integrative analyses highlight functional dynamic gene regulatory networks directing human cardiac development. Holman AR, Tran S, Destici E, Farah EN, Li T, Nelson AC, Engler AJ, Chi NC. Cell Genom. 2024 Nov 13;4(11):100680. doi: 10.1016/j.xgen.2024.100680. Epub 2024 Oct 21. PubMed |
| NANOG governs cell metabolism and redox homeostasis in human naive embryonic stem cells. Shao M, Wang H, Liu Y, Wang Y, Zhao H, Gu J, Zhong N, Zhou Y, Yin H, Jin Y, Liao B. EMBO Rep. 2025 Dec;26(24):6292-6324. doi: 10.1038/s44319-025-00629-9. Epub 2025 Nov 19. PubMed |
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