pcDNA flag PPAR gamma Citations (27)

Originally described in: Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation.
Hauser S, Adelmant G, Sarraf P, Wright HM, Mueller E, Spiegelman BM J Biol Chem. 2000 Jun 16. 275(24):18527-33. PubMed Journal

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Articles Citing pcDNA flag PPAR gamma

Articles
Transcriptional coactivator EDF-1 is required for PPARgamma-stimulated adipogenesis. Leidi M, Mariotti M, Maier JA. Cell Mol Life Sci. 2009 Aug . 66(16):2733-42. PubMed
Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton. Almeida M, Ambrogini E, Han L, Manolagas SC, Jilka RL. J Biol Chem. 2009 Oct 2;284(40):27438-48. doi: 10.1074/jbc.M109.023572. Epub 2009 Aug 5. PubMed
Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27. Flach RJ, Qin H, Zhang L, Bennett AM. J Biol Chem. 2011 Jun 24;286(25):22195-202. doi: 10.1074/jbc.M110.210237. Epub 2011 Apr 26. PubMed
Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor gamma2 expression. Ahn YH, Yang Y, Gibbons DL, Creighton CJ, Yang F, Wistuba II, Lin W, Thilaganathan N, Alvarez CA, Roybal J, Goldsmith EJ, Tournier C, Kurie JM. Mol Cell Biol. 2011 Nov;31(21):4270-85. doi: 10.1128/MCB.05562-11. Epub 2011 Sep 6. PubMed
Transcriptional regulation of flotillins by the extracellularly regulated kinases and retinoid X receptor complexes. Banning A, Ockenga W, Finger F, Siebrasse P, Tikkanen R. PLoS One. 2012;7(9):e45514. doi: 10.1371/journal.pone.0045514. Epub 2012 Sep 18. PubMed
Construction of a doxycycline inducible adipogenic lentiviral expression system. Liu Q, Hill PJ, Karamitri A, Ryan KJ, Chen HY, Lomax MA. Plasmid. 2013 Jan;69(1):96-103. doi: 10.1016/j.plasmid.2012.10.001. Epub 2012 Oct 23. PubMed
PPARgamma maintains ERBB2-positive breast cancer stem cells. Wang X, Sun Y, Wong J, Conklin DS. Oncogene. 2013 Dec 5;32(49):5512-21. doi: 10.1038/onc.2013.217. Epub 2013 Jun 17. PubMed
Cubilin expression is monoallelic and epigenetically augmented via PPARs. Aseem O, Barth JL, Klatt SC, Smith BT, Argraves WS. BMC Genomics. 2013 Jun 18;14:405. doi: 10.1186/1471-2164-14-405. PubMed
Differentiation potential and profile of nuclear receptor expression during expanded culture of human adipose tissue-derived stem cells reveals PPARgamma as an important regulator of Oct4 expression. Dao LT, Park EY, Hwang OK, Cha JY, Jun HS. Stem Cells Dev. 2014 Jan 1;23(1):24-33. doi: 10.1089/scd.2013.0137. Epub 2013 Oct 4. PubMed
Targeted purification of SnAvi-tagged proteins. Schaffer U, Baumeister R, Schulze E. Methods Mol Biol. 2014;1177:163-74. doi: 10.1007/978-1-4939-1034-2_13. PubMed
Creatine inhibits adipogenesis by downregulating insulin-induced activation of the phosphatidylinositol 3-kinase signaling pathway. Lee N, Kim I, Park S, Han D, Ha S, Kwon M, Kim J, Byun SH, Oh W, Jeon HB, Kweon DH, Cho JY, Yoon K. Stem Cells Dev. 2015 Apr 15;24(8):983-94. doi: 10.1089/scd.2014.0130. Epub 2014 Dec 31. PubMed
Histone H3 K27 acetylation marks a potent enhancer element on the adipogenic master regulator gene Pparg2. Ramlee MK, Zhang Q, Idris M, Peng X, Sim CK, Han W, Xu F. Cell Cycle. 2014;13(21):3414-22. doi: 10.4161/15384101.2014.953424. PubMed
G Protein-Coupled Receptor 40 (GPR40) and Peroxisome Proliferator-Activated Receptor gamma (PPARgamma): An Integrated Two-Receptor Signaling Pathway. Wang S, Awad KS, Elinoff JM, Dougherty EJ, Ferreyra GA, Wang JY, Cai R, Sun J, Ptasinska A, Danner RL. J Biol Chem. 2015 Jun 23. pii: jbc.M115.638924. PubMed
CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor alpha in Human Liver. Makia NL, Goldstein JA. Mol Pharmacol. 2016 Jan;89(1):154-64. doi: 10.1124/mol.115.100255. Epub 2015 Oct 14. PubMed
PPAR-delta is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. Dickey AS, Pineda VV, Tsunemi T, Liu PP, Miranda HC, Gilmore-Hall SK, Lomas N, Sampat KR, Buttgereit A, Torres MJ, Flores AL, Arreola M, Arbez N, Akimov SS, Gaasterland T, Lazarowski ER, Ross CA, Yeo GW, Sopher BL, Magnuson GK, Pinkerton AB, Masliah E, La Spada AR. Nat Med. 2016 Jan;22(1):37-45. doi: 10.1038/nm.4003. Epub 2015 Dec 7. PubMed
Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-gamma maintains the epithelial phenotype and antagonizes renal fibrogenesis. Zhao M, Chen Y, Ding G, Xu Y, Bai M, Zhang Y, Jia Z, Huang S, Zhang A. Oncotarget. 2016 Oct 4;7(40):64690-64701. doi: 10.18632/oncotarget.11811. PubMed
The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia. Chakraborty K, Raundhal M, Chen BB, Morse C, Tyurina YY, Khare A, Oriss TB, Huff R, Lee JS, St Croix CM, Watkins S, Mallampalli RK, Kagan VE, Ray A, Ray P. Nat Commun. 2017 Jan 11;8:13944. doi: 10.1038/ncomms13944. PubMed
A novel interaction of PAK4 with PPARgamma to regulate Nox1 and radiation-induced epithelial-to-mesenchymal transition in glioma. Kesanakurti D, Maddirela D, Banasavadi-Siddegowda YK, Lai TH, Qamri Z, Jacob NK, Sampath D, Mohanam S, Kaur B, Puduvalli VK. Oncogene. 2017 Sep 14;36(37):5309-5320. doi: 10.1038/onc.2016.261. Epub 2017 May 22. PubMed
Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation. Dutta D, Lai KY, Reyes-Ordonez A, Chen J, van der Donk WA. J Lipid Res. 2018 Aug;59(8):1433-1445. doi: 10.1194/jlr.M085274. Epub 2018 Jun 7. PubMed
The Nuclear Receptor PPARgamma Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory. Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, Balint BL, Sweeney HL, Nagy L. Immunity. 2018 Oct 16;49(4):615-626.e6. doi: 10.1016/j.immuni.2018.09.005. PubMed
Adipocyte OGT governs diet-induced hyperphagia and obesity. Li MD, Vera NB, Yang Y, Zhang B, Ni W, Ziso-Qejvanaj E, Ding S, Zhang K, Yin R, Wang S, Zhou X, Fang EX, Xu T, Erion DM, Yang X. Nat Commun. 2018 Nov 30;9(1):5103. doi: 10.1038/s41467-018-07461-x. PubMed
Rosiglitazone-dependent dissociation of HuR from PPAR-gamma regulates adiponectin expression at the posttranscriptional level. Hwang JS, Lee WJ, Hur J, Lee HG, Kim E, Lee GH, Choi MJ, Lim DS, Paek KS, Seo HG. FASEB J. 2019 Jun;33(6):7707-7720. doi: 10.1096/fj.201802643R. Epub 2019 Mar 21. PubMed
Cluh plays a pivotal role during adipogenesis by regulating the activity of mitochondria. Cho E, Jung W, Joo HY, Park ER, Kim MY, Kim SB, Kim KS, Lim YB, Lee KH, Shin HJ. Sci Rep. 2019 May 2;9(1):6820. doi: 10.1038/s41598-019-43410-4. PubMed
Cardiolipin-mediated PPARgamma S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia. Garg M, Johri S, Sagar S, Mundhada A, Agrawal A, Ray P, Chakraborty K. Cell Rep. 2021 Feb 9;34(6):108736. doi: 10.1016/j.celrep.2021.108736. PubMed
Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake. Habtemichael EN, Li DT, Camporez JP, Westergaard XO, Sales CI, Liu X, Lopez-Giraldez F, DeVries SG, Li H, Ruiz DM, Wang KY, Sayal BS, Gonzalez Zapata S, Dann P, Brown SN, Hirabara S, Vatner DF, Goedeke L, Philbrick W, Shulman GI, Bogan JS. Nat Metab. 2021 Mar;3(3):378-393. doi: 10.1038/s42255-021-00359-x. Epub 2021 Mar 8. PubMed
SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARgamma. Khan D, Ara T, Ravi V, Rajagopal R, Tandon H, Parvathy J, Gonzalez EA, Asirvatham-Jeyaraj N, Krishna S, Mishra S, Raghu S, Bhati AS, Tamta AK, Dasgupta S, Kolthur-Seetharam U, Etchegaray JP, Mostoslavsky R, Rao PSM, Srinivasan N, Sundaresan NR. Cell Rep. 2021 Jun 1;35(9):109190. doi: 10.1016/j.celrep.2021.109190. PubMed
Epigenetic derepression converts PPARgamma into a druggable target in triple-negative and endocrine-resistant breast cancers. Loo SY, Syn NL, Koh AP, Teng JC, Deivasigamani A, Tan TZ, Thike AA, Vali S, Kapoor S, Wang X, Wang JW, Tan PH, Yip GW, Sethi G, Huang RY, Hui KM, Wang L, Goh BC, Kumar AP. Cell Death Discov. 2021 Sep 27;7(1):265. doi: 10.1038/s41420-021-00635-5. PubMed

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