The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers.

Lockwood WW, Chandel SK, Stewart GL, Erdjument-Bromage H, Beverly LJ
PLoS One. 2013 May 2;8(5):e63610. doi: 10.1371/journal.pone.0063610. Print 2013. PubMed Article

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