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Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
Chiou SH, Winters IP, Wang J, Naranjo S, Dudgeon C, Tamburini FB, Brady JJ, Yang D, Gruner BM, Chuang CH, Caswell DR, Zeng H, Chu P, Kim GE, Carpizo DR, Kim SK, Winslow MM
Genes Dev. 2015 Jul 15;29(14):1576-85. doi: 10.1101/gad.264861.115. Epub 2015 Jul 15.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
66894Lenti-sgLkb1/CreExpresses an Lkb1-targeting gRNA and Cre-recombinase
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66895Lenti-sgNT/CreExpresses a non-targeting gRNA and Cre-recombinase
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67594Lenti-sgNeo/CreExpresses an Neomycin-targeting gRNA and Cre-recombinase
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