Loss of ARID1A activates ANXA1, which serves as a predictive biomarker for trastuzumab resistance.

Berns K, Sonnenblick A, Gennissen A, Brohee S, Hijmans ME, Evers B, Fumagalli D, Desmedt C, Loibl S, Denkert C, Neven P, Guo W, Zhang F, Knijnenburg TA, Bosse T, van der Heijden MS, Hindriksen S, Nijkamp W, Wessels LF, Joensuu H, Mills GB, Beijersbergen RL, Sotiriou C, Bernards R
Clin Cancer Res. 2016 May 12. pii: clincanres.2996.2015. PubMed Article

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