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A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo.

Rogers ZN, McFarland CD, Winters IP, Naranjo S, Chuang CH, Petrov D, Winslow MM
Nat Methods. 2017 May 22. doi: 10.1038/nmeth.4297. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
89641Lenti-sgApc/CreExpresses an Apc-targeting gRNA and Cre-recombinase
89642Lenti-sgArid1a/CreExpresses an Arid1a-targeting gRNA and Cre-recombinase
89643Lenti-sgAtm/CreExpresses an Atm-targeting gRNA and Cre-recombinase
89644Lenti-sgCdkn2a/CreExpresses a Cdkn2a-targeting gRNA and Cre-recombinase
89645Lenti-sgKeap1/CreExpresses a Keap1-targeting gRNA and Cre-recombinase
89646Lenti-sgp53/CreExpresses a p53-targeting gRNA and Cre-recombinase
89647Lenti-sgRb1/CreExpresses an Rb1-targeting gRNA and Cre-recombinase
89648Lenti-sgRbm10/CreExpresses an Rbm10-targeting gRNA and Cre-recombinase
89649Lenti-sgSetd2#1/CreExpresses a Setd2-targeting gRNA and Cre-recombinase
89650Lenti-sgSetd2#2/CreExpresses a Setd2-targeting gRNA and Cre-recombinase
89651Lenti-sgSmad4/CreExpresses a Smad4-targeting gRNA and Cre-recombinase
89652Lenti-sgNeo2/CreExpresses a Neomycin-targeting gRNA and Cre-recombinase
89653Lenti-sgNeo3/CreExpresses a Neomycin-targeting gRNA and Cre-recombinase
89654Lenti-sgNT3/CreExpresses a non-targeting gRNA and Cre-recombinase

Antibodies from Article