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Can asymmetric post-translational modifications regulate the behavior of STAT3 homodimers?
Letra-Vilela R, Cardoso B, Silva-Almeida C, Maia Rocha A, Murtinheira F, Branco-Santos J, Rodriguez C, Martin V, Santa-Marta M, Herrera F
FASEB Bioadv. 2020 Jan 27;2(2):116-125. doi: 10.1096/fba.2019-00049. eCollection 2020 Feb.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
123164Venus1-WTSTAT3Expresses wild type STAT3 fused to the 1-157 fragment of Venus in mammalian cells
123165Venus2-WTSTAT3Expresses wild type STAT3 fused to the 158-238 fragment of Venus in mammalian cells
123166Venus1-K49R-STAT3Expresses K49R STAT3 fused to the 1-157 fragment of Venus in mammalian cells
123167Venus2-K49R-STAT3Expresses K49R STAT3 fused to the 158-238 fragment of Venus in mammalian cells
123168Venus1-K140R-STAT3Expresses K140R STAT3 fused to the 1-157 fragment of Venus in mammalian cells
123169Venus2-K140R-STAT3Expresses K140R STAT3 fused to the 158-238 fragment of Venus in mammalian cells
123170Venus1-K685R-STAT3Expresses K658R STAT3 fused to the 1-157 fragment of Venus in mammalian cells
123171Venus2-K685R-STAT3Expresses K695R STAT3 fused to the 158-238 fragment of Venus in mammalian cells
123172Venus1-Y705F-STAT3Expresses Y705F STAT3 fused to the 1-157 fragment of Venus in mammalian cells
123173Venus2-Y705F-STAT3Expresses Y705F STAT3 fused to the 158-238 fragment of Venus in mammalian cells
123174Venus1-S727A-STAT3Expresses S727A STAT3 fused to the 1-157 fragment of Venus in mammalian cells
123175Venus2-S727A-STAT3Expresses S727A STAT3 fused to the 158-238 fragment of Venus in mammalian cells
123176Venus1-Y705F/S727A-STAT3Expresses Y705F/S727A STAT3 double mutant fused to the 1-157 fragment of Venus in mammalian cells
123177Venus2-Y705F/S727A-STAT3Expresses Y705F/S727A STAT3 double mutant fused to the 158-238 fragment of Venus in mammalian cells
123178Venus1-DeltaCT-STAT3Expresses a STAT3 deletion mutant (without the C-terminus from SH2 domain) fused to the 1-157 fragment of Venus in mammalian cells
123179Venus2-DeltaCT-STAT3Expresses a STAT3 deletion mutant (without the C-terminus from SH2 domain) fused to the 158-238 fragment of Venus in mammalian cells

Antibodies from Article