Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV
Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31. PubMed Article
Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV
Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 128095 | pGL4.22-PGK1-HRE::dLUC | Hypoxia response element real-time luciferase reporter |
| 128096 | pGL4.22-VEGF-HRE::dLUC | Hypoxia response element real-time luciferase reporter |
| 128097 | PX458-sgEIF4EBP1 | CRISPR gRNA against human EIF4EBP1 (4EBP1) with Cas9 from S. pyogenes and 2A-EGFP |
| 128098 | PX458-sgTSC2 | CRISPR gRNA against human TSC2 with Cas9 from S. pyogenes and 2A-EGFP |
| 128099 | pcDNA3.1+ Flag-RAP2A | Expresses RAP2A in mammalian cells in a G418-selectable plasmid |
| 128101 | pcDNA3.1+ Flag-RAGB99L | Expresses constitutively GTP-bound RAGB in mammalian cells in a G418-selectable plasmid |