Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity.
Richter MF, Zhao KT, Eton E, Lapinaite A, Newby GA, Thuronyi BW, Wilson C, Koblan LW, Zeng J, Bauer DE, Doudna JA, Liu DR
Nat Biotechnol. 2020 Jul;38(7):883-891. doi: 10.1038/s41587-020-0453-z. Epub 2020 Mar 16. PubMed Article
Richter MF, Zhao KT, Eton E, Lapinaite A, Newby GA, Thuronyi BW, Wilson C, Koblan LW, Zeng J, Bauer DE, Doudna JA, Liu DR
Nat Biotechnol. 2020 Jul;38(7):883-891. doi: 10.1038/s41587-020-0453-z. Epub 2020 Mar 16. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 138489 | ABE8e | A-to-G base editor |
| 138490 | ABE8e-dimer | A-to-G base editor |
| 138491 | NG-ABE8e | A-to-G base editor |
| 138492 | CP1028-ABE8e | A-to-G base editor |
| 138493 | CP1041-ABE8e | A-to-G base editor |
| 138494 | ABE8e(TadA-8e V82G) | A-to-G base editor |
| 138495 | ABE8e(TadA-8e V106W) | A-to-G base editor |
| 138496 | ABE8e(TadA-8e K20A R21A) | A-to-G base editor |
| 138497 | NG-ABE8-dimer | A-to-G base editor |
| 138498 | CP1028-ABE8e-dimer | A-to-G base editor |
| 138499 | CP1041-ABE8e-dimer | A-to-G base editor |
| 138500 | SaABE8e | A-to-G base editor |
| 138501 | SaABE8e-dimer | A-to-G base editor |
| 138502 | SaKKH-ABE8e | A-to-G base editor |
| 138503 | SaKKH-ABE8e-dimer | A-to-G base editor |
| 138504 | LbABE8e | A-to-G base editor |
| 138505 | LbABE8e-dimer | A-to-G base editor |
| 138506 | enAsABE8e | A-to-G base editor |
| 138507 | enAsABE8e-dimer | A-to-G base editor |
| 138508 | LbABE8e(TadA-8e V106W) | A-to-G base editor |
| 138509 | SaABE8e(TadA V106W) | A-to-G base editor |
| 138510 | pBT120a17 | P1 |
| 138511 | pBT44c | P2 |
| 138512 | pBT128c | P2 |
| 138513 | pBT138b-pro1 | P3h |
| 138514 | pBT138b-proA | P3g |
| 138515 | pBT138b-proB | P3f |
| 138516 | pBT138b-proD | P3e |
| 138517 | pMR-A-3 | P3a |
| 138518 | pMR-A-4 | P3b |
| 138519 | pMR-A-5 | P3c |
| 138520 | pMR-A-6 | P3d |
| 138521 | pBT29 | phage cloning |
| 138522 | pBT100.164 | phage cloning |
| 138523 | pBT114 | phage cloning |