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Diverse enzymatic activities mediate antiviral immunity in prokaryotes.
Gao L, Altae-Tran H, Bohning F, Makarova KS, Segel M, Schmid-Burgk JL, Koob J, Wolf YI, Koonin EV, Zhang F
Science. 2020 Aug 28;369(6507):1077-1084. doi: 10.1126/science.aba0372. PubMed Article

Plasmids from Article

ID Plasmid Purpose
157879pLG001 (empty vector)Empty vector backbone for defense systems
157880pLG002 (BREX type I)Expresses the BREX type I defense system
157881pLG003 (Druantia type I)Expresses the Druantia type I defense system
157882pLG004 (RT-Abi-P2)Expresses the RT-Abi-P2 defense system
157883pLG005 (Retron-TIR)Expresses the retron-TIR defense system
157884pLG006 (Ec67 retron)Expresses the Ec67 retron defense system
157885pLG007 (Ec86 retron)Expresses the Ec86 retron defense system
157886pLG008 (Ec78 retron)Expresses the Ec78 retron defense system
157887pLG009 (DRT type 1)Expresses the DRT type 1 defense system
157888pLG010 (DRT type 2)Expresses the DRT type 2 defense system
157889pLG011 (DRT type 3)Expresses the DRT type 3 defense system
157890pLG012 (DRT type 4)Expresses the DRT type 4 defense system
157891pLG013 (DRT type 5)Expresses the DRT type 5 defense system
157892pLG014 (RADAR)Expresses the RADAR defense system
157893pLG015 (RADAR)Expresses the RADAR defense system
157894pLG016 (ApeA)Expresses the ApeA defense system
157895pLG017 (AVAST type 1)Expresses the AVAST type 1 defense system
157896pLG018 (AVAST type 2)Expresses the AVAST type 2 defense system
157897pLG019 (AVAST type 3)Expresses the AVAST type 3 defense system
157898pLG020 (AVAST type 4)Expresses the AVAST type 4 defense system
157899pLG021 (AVAST type 5)Expresses the AVAST type 5 defense system
157900pLG022 (dsr1)Expresses the dsr1 defense system
157901pLG023 (dsr2)Expresses the dsr2 defense system
157902pLG024 (SIR2 + HerA)Expresses the SIR2 + HerA defense system
157903pLG025 (DUF4297 + HerA)Expresses the DUF4297 + HerA defense system
157904pLG026 (tmn)Expresses the tmn defense system
157905pLG027 (qatABCD)Expresses the qatABCD defense system
157906pLG028 (hhe)Expresses the hhe defense system
157907pLG029 (mzaABCDE)Expresses the mzaABCDE defense system
157908pLG030 (TerY-P)Expresses the TerY-P defense system
157909pLG031 (upx)Expresses the upx defense system
157910pLG032 (ppl)Expresses the ppl defense system
157911pLG033 (ietAS)Expresses the ietAS defense system
157912pLG034 (restriction-like)Expresses a restriction-like defense system

Antibodies from Article