Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation.
Kulicke CA, Swarbrick GM, Ladd NA, Cansler M, Null M, Worley A, Lemon C, Ahmed T, Bennett J, Lust TN, Heisler CM, Huber ME, Krawic JR, Ankley LM, McBride SK, Tafesse FG, Olive AJ, Hildebrand WH, Lewinsohn DA, Adams EJ, Lewinsohn DM, Harriff MJ
Commun Biol. 2024 Feb 24;7(1):228. doi: 10.1038/s42003-024-05912-4.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 214752 | pCI AscI MR1 res | expresses human MR1 resistant to CRISPR editing with a specific sgRNA in mammalian cells |
| 214753 | pCI AscI MR1 R9H res | expresses human MR1 R9H resistant to CRISPR editing with a specific sgRNA in mammalian cells |