The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Xu P, Liu Y, Liu C, Guey B, Li L, Melenec P, Ricci J, Ablasser A
Nature. 2024 Mar;627(8005):873-879. doi: 10.1038/s41586-024-07112-w. Epub 2024 Feb 28.
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