The bridge-like lipid transport protein VPS13C/PARK23 mediates ER-lysosome contacts following lysosome damage.
Wang X, Xu P, Bentley-DeSousa A, Hancock-Cerutti W, Cai S, Johnson BT, Tonelli F, Shao L, Talaia G, Alessi DR, Ferguson SM, De Camilli P
Nat Cell Biol. 2025 May;27(5):776-789. doi: 10.1038/s41556-025-01653-6. Epub 2025 Apr 10.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 232864 | VPS13C^Halo | Expresses human VPS13C^Halo in mammalian cells |
| 232865 | mCherry-VAB(VPS13C) | Expresses the VAB domain of VPS13C in mammalian cells |
| 232866 | mCherry-VPS13C-Cter | Expresses the C-terminal fragments of VPS13C in mammalian cells |
| 232867 | VPS13C^Halo-△(ATG2C-PH) | Expresses VPS13C-△(ATG2C-PH) in mammalian cells |
| 232868 | mCherry-ATG2C(VPS13C) | Expresses the ATG2C domain of VPS13C in mammalian cells |
| 232869 | mCherry-PH(VPS13C) | Expresses the PH domain of VPS13C in mammalian cells |
| 232870 | Halo-SspB-PPM1H | Expresses SspB-PPM1H in mammalian cells |
| 232871 | mCherry-OSBP | Expresses OSBP in mammalian cells |
| 232872 | GFP-LRRK2 | Expresses LRRK2 in mammalian cells |
| 233585 | mScarlet-PPM1H | Expresses PPM1H in mammalian cells |
| 233586 | mScarlet-LRRK1 K746G | Expresses LRRK1 K746G in mammalian cells |