Ramiro Iglesias-Bartolome Lab: Dissection of Galphas and Hedgehog signaling crosstalk reveals therapeutic opportunities to target adenosine receptor 2b in Hedgehog-dependent tumors.
Krantz S, Bell B, Lund K, Parra NS, Ng Y, De Oliveira Rosa N, Mukhopadhyay S, Croix BS, Sarin KY, Weigert R, Raimondi F, Iglesias-Bartolome R
bioRxiv [Preprint]. 2025 Feb 27:2025.02.21.639530. doi: 10.1101/2025.02.21.639530.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 249268 | pCEFL_GPR161-HA | Expression of GPR161 wild type |
| 249269 | pCEFL_GPR161-HA_V129E | Expression of GPR161 V129E mutant |
| 249281 | pGL4.R_8xGLIBS_minPro_Luc2p_Ren | Dual-luciferase GLI reporter plasmid. 8xGLI binding site followed by minPro-luc2P expression, in addition to constitutive SV-40-driven Renilla luciferase expression. |
| 249282 | pLenti X1 Puro 8xGLI_minPro_Luc2p_Ren | Dual-luciferase GLI reporter viral plasmid. 8xGLI binding site followed by minPro-luc2P expression, in addition to constitutive SV-40-driven Renilla luciferase expression. |