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Core clock protein subcellular dynamics coordinate local and global circadian control in syncytia.

Wang Z, Bartholomai BM, Wang B, Ritz D, Schultz D, Loros JJ, Dunlap JC
J Cell Biol. 2026 Jun 1;225(6):e202509044. doi: 10.1083/jcb.202509044. Epub 2026 May 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
245515frq[mNG_Flag]_hphEndogenous C-terminal tag the circadian clock negative arm component FRQ with condon-optimized mNeonGreen and Flag tag.
245516wc-2[mAp]_hphEndogenous C-terminal tag the circadian clock positive arm component WC-2 with mApple.
245517csr-1_frq[mCherry_V5H6]Epitopically express mCherry-tagged FRQ driven by frq endogenous promoter at csr-1 locus.
245518wc-1[mNG_Flag]_barEndogenous C-terminal tag the circadian clock positive arm component WC-1 with condon-optimized mNeonGreen and Flag tag.

Antibodies from Article