Functional divergence of Capicua isoforms explains differential tissue vulnerability in neurological disease.
Lee H, Gonzalez EV, Rivera EM, Durham MA, Richman R, Chu EH, Xia K, Chen H, Liu Z, Veeraragavan S, Shivanna B, Zoghbi HY
Genes Dev. 2026 Aug 3;40(15-16):1267-1282. doi: 10.1101/gad.353596.125.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 262255 | pcDNA3.1-DEST-hCIC-L-V5 | Expresses CIC-L isoform in mammalian cells |
| 262256 | pcDNA3.1-DEST-hCIC-S-V5 | Expresses CIC-S isoform in mammalian cells |
| 262258 | pcDNA3.1-DEST-hCIC-S-W37A-V5 | Expresses CIC-S isoform with the W37A mutant in mammalian cells |
| 262259 | pcDNA3.1-Flag-hATXN1 | Expresses ATXN1 in mammalian cells |
| 262260 | pLV-EF1a-Flag-hATXN1L | Expresses ATXN1L in mammalian cells |
| 262261 | pcDNA3.1-DEST-V5-hCIC-L-unique | Expresses CIC-L isoform unique N-terminal region in mammalian cells |