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Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells.
Mayr C, Bartel DP
Cell. 2009 Aug 21. 138(4):673-84.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
21639pIS1 IMP-1 short UTR
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21640pIS1 IMP-1 long UTR
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21642pIS1 IMP-1 long-mut-let-7
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21643pIS1 IMP-1 rc
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21644pIS1 Cyclin D2 short UTR
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21645pIS1 Cyclin D2 long UTR
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21646pMSCV Cyclin D2 long-wt
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21647pIS1 Cyclin D2 long-mut-miR15/16
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21648pIS1 DICER1 short UTR
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21649pIS1 DICER1 long UTR
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21651pIS1 DICER1 long-mut-let-7
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21652pIS1 DICER1 long-mut-miR103/107
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21653pIS1 DICER1 long-mut-all
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21654pMSCV PIG (Puro IRES GFP empty vector)Retroviral backbone for cloning and gene expression. Select with puromycin or GFP.
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21655pMSCV Cyclin D2-short
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21657pMSCV Cyclin D2-long-mut
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21659pMSCV PIG IMP-1-short
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21661pMSCV PIG IMP-1-long-mut
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Antibodies from Article