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TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.

Johnson BS, Snead D, Lee JJ, McCaffery JM, Shorter J, Gitler AD

J Biol Chem. 2009 Jul 24. 284(30):20329-39. PubMed Journal

ID Plasmid
27447 pRS416Gal TDP43 WT YFP Add to Cart
27448 pRS416 Gal G294A YFP Add to Cart
27449 pRS416 Gal M337V YFP Add to Cart
27450 pRS416 Gal Q331K YFP Add to Cart
27451 pCold TDP43 WT Add to Cart
27452 pCold TDP43 G294A Add to Cart
27453 pCold TDP43 M337V Add to Cart
27454 pCold TDP43 Q331K Add to Cart
27458 pRS416 Gal TDP43 WT Add to Cart
27459 pRS416 Gal TDP43 G294A Add to Cart
27460 pRS416 Gal TDP43 M337V Add to Cart
27461 pRS416 Gal TDP43 Q331K Add to Cart
27462 pDuet TDP43 WT Add to Cart
27463 pDuet TDP-43 G294A Add to Cart
27464 pDuet TDP-43 M337V Add to Cart
27465 pDuet TDP-43 Q331K Add to Cart