Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling.
Lim CY, Bi X, Wu D, Kim JB, Gunning PW, Hong W, Han W
Nat Commun. 2015 Jan 9;6:5951. doi: 10.1038/ncomms6951. PubMed Article
Lim CY, Bi X, Wu D, Kim JB, Gunning PW, Hong W, Han W
Nat Commun. 2015 Jan 9;6:5951. doi: 10.1038/ncomms6951. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose | |
|---|---|---|---|
| 64048 | pLenti-Lifeact-tdTomato | Fluorescent reporter for F-actin labeling in living cells |
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| 64049 | pLenti-myc-GLUT4-mCherry | 3rd generation lentiviral transfer plasmid. Reporter for GLUT4 translocation |
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| 64050 | pLenti-FLAG-Akt2-CA | Myristoylated-FLAG-tagged Akt2, constitutively active |
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| 70752 | pCMV5-HA-mTmod3-WT | N-terminal-HA-tagged mouse Tropomodulin3, WT |
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| 70753 | pGEX-KG-mTmod3-WT | mouse Tropomodulin3, WT for bacterial expression |
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| 70754 | pGEX-KG-mTmod3-1_163_domain | mouse Tropomodulin3, 1-163 domain for bacterial expression |
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| 70755 | pGEX-KG-mTmod3-150-352_domain | mouse Tropomodulin3, 150-352 domain for bacterial expression |
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| 70756 | pGEX-KG-mTmod3-1-325_domain | mouse Tropomodulin3, 1-325 domain for bacterial expression |
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