CRISPR Plasmids: Epigenetics
To make targeted epigenetic modifications, researchers have fused catalytically dead dCas9 to epigenetic modifiers. Design your gRNA to target a specific promoter or enhancer for your gene of interest.
Available modifications include:
- histone acetylation by p300
- histone demethylation by LSD1
- cytosine methylation by DNMT3A or MQ1
- cytosine demethylation by Tet1
Browse, sort, or search the tables below for CRISPR plasmids for epigenetic modification in mammalian or plant systems.