We narrowed to 11,880 results for: Vars
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Plasmid#125397PurposeCRISPR-mediated repression of human islet enhancer containing T1D/T2D-associated variant rs4237150 (GLIS3 GWAS locus)DepositorInsertKRAB-dCas9-2A-BlastR
UseCRISPR and LentiviralTagsHAExpressionMammalianPromoterhPGK and U6Available SinceJuly 23, 2019AvailabilityAcademic Institutions and Nonprofits only -
Lenti-(BB)-hPGK-KRAB-dCas9-P2A-BlastR rs11257655-guide1
Plasmid#125393PurposeCRISPR-mediated repression of human islet enhancer containing T2D-associated variant rs11257655 (CDC123/CAMK1D GWAS locus)DepositorInsertKRAB-dCas9-2A-BlastR
UseCRISPR and LentiviralTagsHAExpressionMammalianPromoterhPGK and U6Available SinceJuly 23, 2019AvailabilityAcademic Institutions and Nonprofits only -
Lenti-(BB)-hPGK-KRAB-dCas9-P2A-BlastR C2CD4AB-enh1-guide1
Plasmid#125400PurposeCRISPR-mediated repression of human islet enhancer containing T2D-associated variant rs182222907 (C2CD4A/B GWAS locus)DepositorInsertKRAB-dCas9-2A-BlastR
UseCRISPR and LentiviralTagsHAExpressionMammalianPromoterhPGK and U6Available SinceJuly 9, 2019AvailabilityAcademic Institutions and Nonprofits only -
pGCS vector kit
Plasmid Kit#1000000107PurposeGateway destination vectors for high-level expression of mRNAs or proteins in a variety of vertebrate organisms.DepositorApplicationGene Expression and LabelingVector TypeAvian Expression, Mammalian Expression, Xenopus Expression, Zebrafish ExpressionAvailable SinceMay 23, 2017AvailabilityAcademic Institutions and Nonprofits only -
P931_CLYBL-CBX3-Cbh-Zeo-TetO-NAIP2
Plasmid#202761PurposeEncodes four RGC specific transcription factors under the control of a TetOn promoter at the CLYBL safe harborDepositorExpressionMammalianPromoterTetOAvailable SinceFeb. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
ScEnSor Kit
Plasmid Kit#1000000215PurposeTo investigate the intracellular environment of Saccharomyces cerevisiae with a variety of biosensors.DepositorApplicationGene Expression and LabelingVector TypeYeast ExpressionAvailable SinceMay 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
FX cloning Kit
Plasmid Kit#1000000039PurposeUse fragment exchange (FX) cloning to generate constructs for screening protein expression in several organisms with a variety of N- and C-terminal tags.DepositorApplicationCloning and Synthetic Biology, Gene Expression and LabelingVector TypeBacterial Expression, Insect Expression, Mammalian Expression, Xenopus Expression, Yeast ExpressionCloning TypeFX CloningAvailable SinceApril 2, 2014AvailabilityAcademic Institutions and Nonprofits only -
CRISPRecise Kit
Plasmid Kit#1000000235PurposeSet of high-fidelity SpCas9 variants that can be used to efficiently edit targets with practically no detectable off-target effects.DepositorApplicationGenome EditingVector TypeMammalian ExpressionEditing TypeCRISPRAvailable SinceJan. 11, 2024AvailabilityAcademic Institutions and Nonprofits only -
pNLF1-N_PWP1:1-501
Plasmid#210974PurposeMammalian expression of full-length human PWP1. N-terminal NanoLuc luciferase tag.DepositorInsertPWP1:M1-S501 (PWP1 Human)
TagsNanoLuc luciferaseExpressionMammalianMutationE165D F448L G449R not annotated variantsPromoterCMVAvailable SinceMarch 20, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_PWP1:1-501
Plasmid#211189PurposeMammalian expression of full-length human PWP1. N-terminal HiBiT tag.DepositorInsertPWP1:M1-S501 (PWP1 Human)
TagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationE165D F448L G449R not annotated variantsPromoterCMVAvailable SinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only