We narrowed to 2,589 results for: GCG

Showing: 2301 - 2320 of 2589 results

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MAPK12 gRNA (BRDN0001146907)

Plasmid

#77485

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK12

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK12 (MAPK12 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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NFATc1-CRISPR-Nick 1/2 (PX461-EF1a-pSpCas9n(BB)-2A-GFP)

Plasmid

#75238

Purpose

CRISPR/Cas9 NICKASE plasmid against human NFATc1 (1/2)

Depositor

Ria Baumgrass

Article

Gabriel et al J Biol Chem. 2016 Sep 16. pii: jbc.M116.

Insert

sgRNA against NFATc1 (NFATC1 Human)

Use

CRISPR

Available Since

June 8, 2016

Availability

Academic Institutions and Nonprofits only

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MASTL gRNA (BRDN0001148082)

Plasmid

#75987

Purpose

3rd generation lentiviral gRNA plasmid targeting human MASTL

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MASTL (MASTL Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAPK7 gRNA (BRDN0001145053)

Plasmid

#76896

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK7

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK7 (MAPK7 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TYK2 gRNA (BRDN0001147182)

Plasmid

#77247

Purpose

3rd generation lentiviral gRNA plasmid targeting human TYK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TYK2 (TYK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TYRO3 gRNA (BRDN0001147403)

Plasmid

#76229

Purpose

3rd generation lentiviral gRNA plasmid targeting human TYRO3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TYRO3 (TYRO3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ITPKB gRNA (BRDN0001147872)

Plasmid

#76871

Purpose

3rd generation lentiviral gRNA plasmid targeting human ITPKB

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ITPKB (ITPKB Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP3K14 gRNA (BRDN0001144896)

Plasmid

#77737

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP3K14

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP3K14 (MAP3K14 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CDK5R1 gRNA (BRDN0001147589)

Plasmid

#77852

Purpose

3rd generation lentiviral gRNA plasmid targeting human CDK5R1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CDK5R1 (CDK5R1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP3K9 gRNA (BRDN0001146157)

Plasmid

#77309

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP3K9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP3K9 (MAP3K9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DTYMK gRNA (BRDN0001147404)

Plasmid

#77511

Purpose

3rd generation lentiviral gRNA plasmid targeting human DTYMK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DTYMK (DTYMK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgFDX1-1

Plasmid

#251679

Purpose

gRNA to knock out FDX1 in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

FDX1 ferredoxin 1 (FDX1 Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA-NC3

Plasmid

#248559

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA-NC3 TD#417

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Jan. 28, 2026

Availability

Academic Institutions and Nonprofits only

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AAV-EF1α-DIO-DSE-mCherry-PSE-shRNA-Numb

Plasmid

#250238

Purpose

Cre-dependent AAV expressing mCherry and an shRNA targeting Numb under EF1α promoter for selective Numb knockdown

Depositor

Won Do Heo

Article

Shin et al Exp Mol Med. 2025 Aug;57(8):1818-1836. d

Insert

Numb (Numb Mouse)

Use

AAV, Cre/Lox, Mouse Targeting, and RNAi

Expression

Mammalian

Promoter

EF1α

Available Since

Jan. 16, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA2-2

Plasmid

#248524

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA2-2

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Nov. 18, 2025

Availability

Academic Institutions and Nonprofits only

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BPK1520-sgRNA GLB1

Plasmid

#184378

Purpose

Expresses a sgRNA to edit GLB1 gene NM_000404.2_c.907A>G

Depositor

David Gilot

Article

Leclerc et al CRISPR J. 2023 Feb;6(1):17-31. doi: 10.1

Insert

sgRNA targeting GLB1 (GLB1 Human)

Use

CRISPR

Expression

Mammalian

Available Since

Aug. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pRCA893 - pBA904 Puro-T2A-BFP KLF5 g1 CRISPRa guide guide (pRCA594 backbone) 666

Plasmid

#238186

Purpose

Lentiviral CRISPR guide vector expressing a KLF5 sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture

Depositor

Thomas Norman

Article

Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415

Insert

KLF5 sgRNA CRISPRa (KLF5 Synthetic, Human)

Use

CRISPR and Lentiviral

Tags

mTagBFP2

Available Since

Aug. 6, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_2xsgRNAs_BRF2 (pAVA3258)

Plasmid

#239326

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting BRF2

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting BRF2 (BRF2 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_sgRNA_EXOSC10 (pAVA3318)

Plasmid

#239295

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC10

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting EXOSC10 (EXOSC10 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hMAP3K7_2m)-PGKpuro2ABFP-W

Plasmid

#208413

Purpose

Lentiviral gRNA plasmid targeting human MAP3K7 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

MAP3K7 (MAP3K7 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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